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TargetGag-Pol polyprotein [489-587]
LigandBDBM50135843
Substrate/Competitorn/a
Meas. Tech.ChEMBL_159444 (CHEMBL763240)
IC50 2000±n/a nM
Citation Breccia, PBoggetto, NPérez-Fernández, RVan Gool, MTakahashi, MRené, LPrados, PBadet, BReboud-Ravaux, Mde Mendoza, J Dimerization inhibitors of HIV-1 protease based on a bicyclic guanidinium subunit. J Med Chem46:5196-207 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50135843
n/a
NameBDBM50135843
Synonyms:Bicyclic Guanidinium Subunit | CHEMBL216653
TypeSmall organic molecule
Emp. Form.C69H91N10O11SSi
Mol. Mass.1296.671
SMILESCC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)CNC(=O)CSCC1CCN2CCC(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)[NH+]=C2N1)[C@@H](C)OCc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |c:52|
Structure
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