| Reaction Details |
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 | Report a problem with these data |
| Target | Probable G-protein coupled receptor 142 |
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| Ligand | BDBM50440698 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_985961 (CHEMBL2432193) |
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| EC50 | 2780±n/a nM |
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| Citation |  Yu, M; Lizarzaburu, M; Motani, A; Fu, Z; Du, X; Liu, JJ; Jiao, X; Lai, S; Fan, P; Fu, A; Liu, Q; Murakoshi, M; Nara, F; Oda, K; Okuyama, R; Reagan, JD; Watanabe, N; Yamazaki, M; Xiong, Y; Zhang, Y; Zhuang, R; Lin, DC; Houze, JB; Medina, JC; Li, L Aminopyrazole-Phenylalanine Based GPR142 Agonists: Discovery of Tool Compound and in Vivo Efficacy Studies. ACS Med Chem Lett4:829-34 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable G-protein coupled receptor 142 |
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| Name: | Probable G-protein coupled receptor 142 |
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| Synonyms: | G-protein coupled receptor PGR2 | GP142_HUMAN | GPR142 | PGR2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51127.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_985961 |
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| Residue: | 462 |
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| Sequence: | MSIMMLPMEQKIQWVPTSLQDITAVLGTEAYTEEDKSMVSHAQKSQHSCLSHSRWLRSPQ
VTGGSWDLRIRPSKDSSSFRQAQCLRKDPGANNHLESQGVRGTAGDADRELRGPSEKATA
GQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVA
LARLATRTRRPSYYYLLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFA
ANHASVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMW
RDTDSPRTLDEVLKWAHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILL
GITTLFTLLWAPRVFVMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKT
FRATVRQVIHDAYLPCTLASQPEGMAAKPVMEPPGLPTGAEV
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| BDBM50440698 |
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| n/a |
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| Name | BDBM50440698 |
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| Synonyms: | CHEMBL2431064 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N6OS |
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| Mol. Mass. | 430.525 |
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| SMILES | O=C([C@H](Cc1ccccc1)NCc1cncs1)N1CCn2nc(cc12)-c1ccncc1 |r| |
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| Structure | 
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