| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium- and chloride-dependent betaine transporter |
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| Ligand | BDBM50101329 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1454199 (CHEMBL3363499) |
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| IC50 | 590±n/a nM |
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| Citation |  Kobayashi, T; Suemasa, A; Igawa, A; Ide, S; Fukuda, H; Abe, H; Arisawa, M; Minami, M; Shuto, S Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor. ACS Med Chem Lett5:889-93 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium- and chloride-dependent betaine transporter |
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| Name: | Sodium- and chloride-dependent betaine transporter |
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| Synonyms: | Betaine transporter | S6A12_HUMAN | SLC6A12 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 69366.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1454199 |
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| Residue: | 614 |
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| Sequence: | MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVW
RFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGL
ASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTP
FENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVY
FTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQG
CLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGP
GLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGR
RELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADR
FYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGW
FLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSP
TREGLIAGEKETHL
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| BDBM50101329 |
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| n/a |
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| Name | BDBM50101329 |
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| Synonyms: | CHEMBL3326391 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H11NO2 |
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| Mol. Mass. | 141.1677 |
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| SMILES | [H][C@@]12C[C@]1(N)CC[C@@H]2C(O)=O |r| |
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| Structure | 
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