Reaction Details | |||
---|---|---|---|
![]() | Report a problem with these data | ||
Target | Potassium voltage-gated channel subfamily H member 2 | ||
Ligand | BDBM50113642 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1510551 (CHEMBL3607786) | ||
IC50 | 2400±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Potassium voltage-gated channel subfamily H member 2 | |||
Name: | Potassium voltage-gated channel subfamily H member 2 | ||
Synonyms: | 1,3-beta-glucan synthase component GLS2 | Cytochrome P450 3A4 | ERG | ERG1 | Eag-related protein 1 | Ether a-go-go related gene potassium channel (hERG) | Ether-a-go-go-related gene (HERG) | Ether-a-go-go-related gene potassium channel (hERG) | Ether-a-go-go-related gene potassium channel 1 | Ether-a-go-go-related gene potassium channel 1 (HERG) | Ether-a-go-go-related gene potassium channel 1 (hERG1) | Ether-a-go-go-related protein (hERG) | Ether-a-go-go-related protein 1 | Ether-a-go-go-related protein 1 (HERG) | H-ERG | HERG | KCNH2 | KCNH2_HUMAN | Potassium voltage-gated channel subfamily H member 2 (hERG) | Transcriptional regulator ERG | Voltage-gated potassium channel subunit Kv11.1 | eag homolog | hERG Potassium Channel 1 | putative potassium channel subunit | ||
Type: | Multi-pass membrane protein | ||
Mol. Mass.: | 126672.65 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q12809 | ||
Residue: | 1159 | ||
Sequence: |
| ||
BDBM50113642 | |||
n/a | |||
Name | BDBM50113642 | ||
Synonyms: | CHEMBL3604801 | ||
Type | Small organic molecule | ||
Emp. Form. | C30H34FN5O6 | ||
Mol. Mass. | 579.6193 | ||
SMILES | CCOC(=O)C1(C)Oc2ccc(CNC34CCC(CCc5c(F)cnc6ccc(OC)nc56)(CC3)OC4)nc2NC1=O |(3.88,17.8,;5.08,18.08,;6.14,16.95,;7.64,17.3,;8,18.48,;8.71,16.22,;9.92,16.47,;7.21,15.87,;6.76,14.39,;5.26,14.05,;4.8,12.56,;5.86,11.44,;5.41,9.96,;3.9,9.61,;3.46,8.16,;4.56,7.06,;4.17,5.57,;2.68,5.4,;2.67,3.85,;1.34,3.08,;1.33,1.54,;2.67,.77,;3.74,1.39,;2.67,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-2.69,-.77,;-2.69,.77,;-4.02,1.54,;-4.02,2.78,;-1.33,1.54,;,.77,;2.27,6.67,;3.81,6.67,;1.58,6.27,;1.98,7.74,;7.37,11.8,;7.81,13.27,;9.31,13.62,;9.76,15.09,;10.96,15.37,)| | ||
Structure | ![]() |