Reaction Details | |||
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Target | Serine/threonine-protein kinase B-raf | ||
Ligand | BDBM50485028 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_816295 (CHEMBL2026971) | ||
IC50 | 3.0±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Serine/threonine-protein kinase B-raf | |||
Name: | Serine/threonine-protein kinase B-raf | ||
Synonyms: | B-RAF | B-Raf Protein Kinase | B-Raf proto-oncogene serine/threonine-protein kinase | BRAF | BRAF1 | BRAF_HUMAN | RAFB1 | p94 | v-Raf murine sarcoma viral oncogene homolog B1 | ||
Type: | Serine/threonine-protein kinase | ||
Mol. Mass.: | 84446.00 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P15056 | ||
Residue: | 766 | ||
Sequence: |
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BDBM50485028 | |||
n/a | |||
Name | BDBM50485028 | ||
Synonyms: | CHEMBL2023501 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H20F2N6O3S | ||
Mol. Mass. | 486.494 | ||
SMILES | CCCS(=O)(=O)Nc1ccc(F)c(c1F)-c1cc2cnc(Nc3cccnc3)nc2n(C)c1=O |(39.5,-24.7,;38.16,-23.92,;36.83,-24.7,;35.5,-23.93,;34.72,-22.59,;36.26,-22.59,;34.17,-24.71,;32.84,-23.94,;32.83,-22.39,;31.49,-21.63,;30.16,-22.39,;28.83,-21.63,;30.16,-23.94,;31.5,-24.71,;31.5,-26.25,;28.83,-24.71,;27.5,-23.93,;26.17,-24.7,;24.84,-23.92,;23.52,-24.69,;23.52,-26.23,;22.18,-27,;20.85,-26.23,;19.53,-27,;18.19,-26.24,;18.19,-24.7,;19.52,-23.92,;20.86,-24.69,;24.84,-26.99,;26.16,-26.23,;27.5,-27,;27.5,-28.54,;28.83,-26.24,;30.17,-27,)| | ||
Structure | ![]() |