| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50504810 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1816841 (CHEMBL4316415) |
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| Ki | 505±n/a nM |
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| Citation |  Staro?, J; Kurczab, R; Warszycki, D; Sata?a, G; Krawczyk, M; Bugno, R; Lenda, T; Popik, P; Hogendorf, AS; Hogendorf, A; Dubiel, K; Mat?oka, M; Moszczy?ski-P?tkowski, R; Pieczykolan, J; Wieczorek, M; Zajdel, P; Bojarski, AJ Virtual screening-driven discovery of dual 5-HT Eur J Med Chem185:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50504810 |
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| n/a |
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| Name | BDBM50504810 |
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| Synonyms: | CHEMBL4442855 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18FN3O2 |
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| Mol. Mass. | 351.3742 |
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| SMILES | Oc1ccc(cc1)-c1ccc(CNCCc2c[nH]c3ncc(F)cc23)o1 |
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| Structure | 
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