| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
|---|
| Ligand | BDBM50504810 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1816837 (CHEMBL4316411) |
|---|
| Ki | 25±n/a nM |
|---|
| Citation |  Staro?, J; Kurczab, R; Warszycki, D; Sata?a, G; Krawczyk, M; Bugno, R; Lenda, T; Popik, P; Hogendorf, AS; Hogendorf, A; Dubiel, K; Mat?oka, M; Moszczy?ski-P?tkowski, R; Pieczykolan, J; Wieczorek, M; Zajdel, P; Bojarski, AJ Virtual screening-driven discovery of dual 5-HT Eur J Med Chem185:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 6 |
|---|
| Name: | 5-hydroxytryptamine receptor 6 |
|---|
| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 46968.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P50406 |
|---|
| Residue: | 440 |
|---|
| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
|
|
|
|---|
| BDBM50504810 |
|---|
| n/a |
|---|
| Name | BDBM50504810 |
|---|
| Synonyms: | CHEMBL4442855 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H18FN3O2 |
|---|
| Mol. Mass. | 351.3742 |
|---|
| SMILES | Oc1ccc(cc1)-c1ccc(CNCCc2c[nH]c3ncc(F)cc23)o1 |
|---|
| Structure | 
|
|---|
Search and Browse
