| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Estrogen receptor beta |
|---|
| Ligand | BDBM50298237 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2063901 (CHEMBL4719154) |
|---|
| EC50 | 7.1±n/a nM |
|---|
| Citation |  Yonekubo, S; Fushimi, N; Miyagi, T; Nakanishi, O; Katsuno, K; Ozawa, M; Handa, C; Furuya, N; Muranaka, H Synthesis and structure-activity relationships of 1-benzylindane derivatives as selective agonists for estrogen receptor beta. Bioorg Med Chem24:5895-5910 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Estrogen receptor beta |
|---|
| Name: | Estrogen receptor beta |
|---|
| Synonyms: | ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 59238.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q92731 |
|---|
| Residue: | 530 |
|---|
| Sequence: | MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
CKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
|
|
|
|---|
| BDBM50298237 |
|---|
| n/a |
|---|
| Name | BDBM50298237 |
|---|
| Synonyms: | 1,2-Bis-(4-hydroxy-phenyl)-ethane | 4,4'-(ethane-1,2-diyl)diphenol | CHEMBL577241 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H14O2 |
|---|
| Mol. Mass. | 214.2598 |
|---|
| SMILES | Oc1ccc(CCc2ccc(O)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
