| Reaction Details |
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 | Report a problem with these data |
| Target | Probable G-protein coupled receptor 142 |
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| Ligand | BDBM50440693 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_985965 (CHEMBL2432197) |
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| EC50 | 31±n/a nM |
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| Citation |  Yu, M; Lizarzaburu, M; Motani, A; Fu, Z; Du, X; Liu, JJ; Jiao, X; Lai, S; Fan, P; Fu, A; Liu, Q; Murakoshi, M; Nara, F; Oda, K; Okuyama, R; Reagan, JD; Watanabe, N; Yamazaki, M; Xiong, Y; Zhang, Y; Zhuang, R; Lin, DC; Houze, JB; Medina, JC; Li, L Aminopyrazole-Phenylalanine Based GPR142 Agonists: Discovery of Tool Compound and in Vivo Efficacy Studies. ACS Med Chem Lett4:829-34 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable G-protein coupled receptor 142 |
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| Name: | Probable G-protein coupled receptor 142 |
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| Synonyms: | GP142_MOUSE | Gpr142 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40779.27 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_985965 |
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| Residue: | 365 |
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| Sequence: | MHLNSNPNSYICDAYQHADLLWSLSPHVLTKAVQPQVTLLPTVNGSNPRYDGVDGHWPES
PERSPCVAGIIPVIYYSVLLSLGLPVALARLAARTRKPSYHYLLALTASDIVTQVIIVFV
GFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPG
RTHRAIAAVIGVTLLTGIPFYWWLDVWRDADPPSTMDKLLKWAHCLIVYFIPCNVFLVTN
SAIILRLRKRGQRGLRPLVSKSTAILLGVTSLFALLWAPRIIVMLYHLYVAPVHRDWRVH
LALDIANMLAMLNTEVNFGLYCFISKTFRATVRQVICDVHMACALKSQPKQTVVELMLKS
VGTEL
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| BDBM50440693 |
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| n/a |
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| Name | BDBM50440693 |
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| Synonyms: | CHEMBL2430983 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N5O3 |
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| Mol. Mass. | 379.4124 |
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| SMILES | Cn1nc(cc1NC(=O)[C@H](Cc1ccccc1)NCC(O)=O)-c1ccncc1 |r| |
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| Structure | 
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