| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial |
|---|
| Ligand | BDBM267938 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence based hOGA assay |
|---|
| pH | 7±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| Ki | 2.80±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Kaul, R; McEachern, EJ; Vocadlo, DJ; Zhou, Y; Liu, K; Selnick, HG; Wei, Z; Mu, C; Wang, Y; Wang, X Selective glycosidase inhibitors and uses thereof US Patent US9718854 Publication Date 8/1/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 4-hydroxy-2-oxoglutarate aldolase, mitochondrial |
|---|
| Name: | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial |
|---|
| Synonyms: | 2-keto-4-hydroxyglutarate aldolase | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial | C10orf65 | DHDPS-like protein | DHDPSL | Dihydrodipicolinate synthase-like, mitochondrial | HOGA1 | HOGA1_HUMAN | Probable KHG-aldolase | Protein 569272 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35253.21 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_461876 |
|---|
| Residue: | 327 |
|---|
| Sequence: | MLGPQVWSSVRQGLSRSLSRNVGVWASGEGKKVDIAGIYPPVTTPFTATAEVDYGKLEEN
LHKLGTFPFRGFVVQGSNGEFPFLTSSERLEVVSRVRQAMPKNRLLLAGSGCESTQATVE
MTVSMAQVGADAAMVVTPCYYRGRMSSAALIHHYTKVADLSPIPVVLYSVPANTGLDLPV
DAVVTLSQHPNIVGMKDSGGDVTRIGLIVHKTRKQDFQVLAGSAGFLMASYALGAVGGVC
ALANVLGAQVCQLERLCCTGQWEDAQKLQHRLIEPNAAVTRRFGIPGLKKIMDWFGYYGG
PCRAPLQELSPAEEEALRMDFTSNGWL
|
|
|
|---|
| BDBM267938 |
|---|
| n/a |
|---|
| Name | BDBM267938 |
|---|
| Synonyms: | (3aR,5R,6S,7R,7aR)-2- (methylamino)-5- ((methylamino)methyl)-5,6,7,7a- tetrahydro-3aH-pyrano[3,2-d]thiazole- 6,7-diol | US9718854, 21 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H17N3O3S |
|---|
| Mol. Mass. | 247.315 |
|---|
| SMILES | CNC[C@H]1O[C@@H]2SC(NC)=N[C@@H]2[C@@H](O)[C@@H]1O |r,c:9| |
|---|
| Structure | 
|
|---|
Search and Browse
