| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50252364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1684649 |
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| Ki | 88±n/a nM |
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| Citation |  ?a?ewska, D; Kurczab, R; Wi?cek, M; Kami?ska, K; Sata?a, G; Jastrz?bska-Wi?sek, M; Partyka, A; Bojarski, AJ; Weso?owska, A; Kie?-Kononowicz, K; Handzlik, J The computer-aided discovery of novel family of the 5-HT Eur J Med Chem135:117-124 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50252364 |
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| n/a |
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| Name | BDBM50252364 |
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| Synonyms: | CHEMBL4079150 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19FN6 |
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| Mol. Mass. | 302.35 |
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| SMILES | CN1CCN(CC1)c1nc(N)nc(Cc2ccccc2F)n1 |
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| Structure | 
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