Compile Data Set for Download or QSAR

Found 266 hits with Last Name = 'wi?cek' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28583 (5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...) Show SMILES COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCNCC1 Show InChI InChI=1S/C20H22ClN3O3S2/c1-13-16-11-14(21)3-6-19(16)28-20(13)29(25,26)23-15-4-5-18(27-2)17(12-15)24-9-7-22-8-10-24/h3-6,11-12,22-23H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells after 1 hr by liquid scintillation counting method				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50419052 (SB-399885) Show SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)Nc1cc(Cl)cc(Cl)c1OC Show InChI InChI=1S/C18H21Cl2N3O4S/c1-26-17-4-3-13(11-16(17)23-7-5-21-6-8-23)28(24,25)22-15-10-12(19)9-14(20)18(15)27-2/h3-4,9-11,21-22H,5-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	0.724	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50274767 (CHEMBL4125735) Show SMILES Clc1cccc(c1)S(=O)(=O)n1ccc2c(N[C@H]3CCNC3)nc3ccccc3c12 |r| Show InChI InChI=1S/C21H19ClN4O2S/c22-14-4-3-5-16(12-14)29(27,28)26-11-9-18-20(26)17-6-1-2-7-19(17)25-21(18)24-15-8-10-23-13-15/h1-7,9,11-12,15,23H,8,10,13H2,(H,24,25)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM35254 (2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...) Show SMILES CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human D2L receptor expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516529 (CHEMBL4520796) Show SMILES CC(C)c1ccc(C)cc1OCc1nc(N)nc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C19H28N6O/c1-13(2)15-6-5-14(3)11-16(15)26-12-17-21-18(20)23-19(22-17)25-9-7-24(4)8-10-25/h5-6,11,13H,7-10,12H2,1-4H3,(H2,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-Methylhistamine from recombinant human histamine H3 receptor expressed in human HEK293 cells incubated for 90 mins by mic...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells assessed as inhibitory constant incubated for 1 hr by radioligand binding...				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516514 (CHEMBL4515075) Show SMILES CC(Sc1ccccc1Cl)c1nc(N)nc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C16H21ClN6S/c1-11(24-13-6-4-3-5-12(13)17)14-19-15(18)21-16(20-14)23-9-7-22(2)8-10-23/h3-6,11H,7-10H2,1-2H3,(H2,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells assessed as inhibitory constant incubated for 1 hr by radioligand bi...				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM189352 (4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2cccc3ccccc23)n1 Show InChI InChI=1S/C19H22N6/c1-24-9-11-25(12-10-24)19-22-17(21-18(20)23-19)13-15-7-4-6-14-5-2-3-8-16(14)15/h2-8H,9-13H2,1H3,(H2,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252344 (CHEMBL4086515) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2c[nH]c3ccccc23)n1 Show InChI InChI=1S/C17H21N7/c1-23-6-8-24(9-7-23)17-21-15(20-16(18)22-17)10-12-11-19-14-5-3-2-4-13(12)14/h2-5,11,19H,6-10H2,1H3,(H2,18,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516522 (CHEMBL4447416) Show SMILES CC(Oc1ccccc1Cl)c1nc(N)nc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C16H21ClN6O/c1-11(24-13-6-4-3-5-12(13)17)14-19-15(18)21-16(20-14)23-9-7-22(2)8-10-23/h3-6,11H,7-10H2,1-2H3,(H2,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516521 (CHEMBL4557247) Show SMILES CN1CCN(CC1)c1nc(N)nc(CSc2ccccc2)n1 Show InChI InChI=1S/C15H20N6S/c1-20-7-9-21(10-8-20)15-18-13(17-14(16)19-15)11-22-12-5-3-2-4-6-12/h2-6H,7-11H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252358 (CHEMBL4104479) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2cccc(Cl)c2)n1 Show InChI InChI=1S/C15H19ClN6/c1-21-5-7-22(8-6-21)15-19-13(18-14(17)20-15)10-11-3-2-4-12(16)9-11/h2-4,9H,5-8,10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252350 (CHEMBL4080312) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2cccc(C)c2)n1 Show InChI InChI=1S/C16H22N6/c1-12-4-3-5-13(10-12)11-14-18-15(17)20-16(19-14)22-8-6-21(2)7-9-22/h3-5,10H,6-9,11H2,1-2H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252356 (CHEMBL4103397) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccc(Cl)c(Cl)c2)n1 Show InChI InChI=1S/C15H18Cl2N6/c1-22-4-6-23(7-5-22)15-20-13(19-14(18)21-15)9-10-2-3-11(16)12(17)8-10/h2-3,8H,4-7,9H2,1H3,(H2,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252357 (CHEMBL4075727) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccc(Cl)cc2)n1 Show InChI InChI=1S/C15H19ClN6/c1-21-6-8-22(9-7-21)15-19-13(18-14(17)20-15)10-11-2-4-12(16)5-3-11/h2-5H,6-10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50090528 (4-Amino-N-(2,6-bis-dimethylamino-pyrimidin-4-yl)-b...) Show SMILES CNc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(NC)n1 Show InChI InChI=1S/C12H16N6O2S/c1-14-10-7-11(17-12(15-2)16-10)18-21(19,20)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H3,14,15,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Binding affinity to human 5HT6R				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556119 (CHEMBL4757387) Show SMILES CC1CCCN(CCCCCOc2ccc3oc4cc(Cl)ccc4c(=O)c3c2)C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252379 (CHEMBL4077077) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccccc2Cl)n1 Show InChI InChI=1S/C15H19ClN6/c1-21-6-8-22(9-7-21)15-19-13(18-14(17)20-15)10-11-4-2-3-5-12(11)16/h2-5H,6-10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252352 (CHEMBL4059916) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2cccc(F)c2)n1 Show InChI InChI=1S/C15H19FN6/c1-21-5-7-22(8-6-21)15-19-13(18-14(17)20-15)10-11-3-2-4-12(16)9-11/h2-4,9H,5-8,10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252349 (CHEMBL4079397) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccc(C)cc2)n1 Show InChI InChI=1S/C16H22N6/c1-12-3-5-13(6-4-12)11-14-18-15(17)20-16(19-14)22-9-7-21(2)8-10-22/h3-6H,7-11H2,1-2H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50053435 (CHEMBL3323035) Show SMILES C(COc1ccc2N=C3CCCN3Cc2c1)CN1CCCCC1 |t:7| Show InChI InChI=1S/C19H27N3O/c1-2-9-21(10-3-1)11-5-13-23-17-7-8-18-16(14-17)15-22-12-4-6-19(22)20-18/h7-8,14H,1-6,9-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-Histamine from human histamine H3 receptor expressed in Sf9 cells incubated for 60 mins by liquid scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252362 (CHEMBL4098336) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccccc2C)n1 Show InChI InChI=1S/C16H22N6/c1-12-5-3-4-6-13(12)11-14-18-15(17)20-16(19-14)22-9-7-21(2)8-10-22/h3-6H,7-11H2,1-2H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556131 (CHEMBL4789324) Show SMILES Clc1ccc2c(c1)oc1ccc(OCCCCCN3CCCCCC3)cc1c2=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516525 (CHEMBL4570584) Show SMILES CN1CCN(CC1)c1nc(N)nc(COc2ccccc2C)n1 Show InChI InChI=1S/C16H22N6O/c1-12-5-3-4-6-13(12)23-11-14-18-15(17)20-16(19-14)22-9-7-21(2)8-10-22/h3-6H,7-11H2,1-2H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252364 (CHEMBL4079150) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccccc2F)n1 Show InChI InChI=1S/C15H19FN6/c1-21-6-8-22(9-7-21)15-19-13(18-14(17)20-15)10-11-4-2-3-5-12(11)16/h2-5H,6-10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM189353 (4-Benzyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-...) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccccc2)n1 Show InChI InChI=1S/C15H20N6/c1-20-7-9-21(10-8-20)15-18-13(17-14(16)19-15)11-12-5-3-2-4-6-12/h2-6H,7-11H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556127 (CHEMBL4777210) Show SMILES CC1CCN(CCCCCCOc2ccc3oc4ccccc4c(=O)c3c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556121 (CHEMBL4796334) Show SMILES CC1CCCN(CCCCCCOc2ccc3oc4ccccc4c(=O)c3c2)C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252351 (CHEMBL4088170) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccc(F)cc2)n1 Show InChI InChI=1S/C15H19FN6/c1-21-6-8-22(9-7-21)15-19-13(18-14(17)20-15)10-11-2-4-12(16)5-3-11/h2-5H,6-10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556132 (CHEMBL4783624) Show SMILES Clc1ccc2oc3ccc(OCCCCCN4CCCCCC4)cc3c(=O)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556124 (CHEMBL4797681) Show SMILES CC1CCN(CCCCCOc2ccc3oc4ccccc4c(=O)c3c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516518 (CHEMBL4462404) Show SMILES [#6]-[#6]([Se;v2]c1ccccc1)-c1nc(-[#7])nc(n1)-[#7]-1-[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1 Show InChI InChI=1S/C16H22N6Se/c1-12(23-13-6-4-3-5-7-13)14-18-15(17)20-16(19-14)22-10-8-21(2)9-11-22/h3-7,12H,8-11H2,1-2H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516523 (CHEMBL4522568) Show SMILES CC(Oc1cccc(Cl)c1)c1nc(N)nc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C16H21ClN6O/c1-11(24-13-5-3-4-12(17)10-13)14-19-15(18)21-16(20-14)23-8-6-22(2)7-9-23/h3-5,10-11H,6-9H2,1-2H3,(H2,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516528 (CHEMBL4591878) Show SMILES CN1CCN(CC1)c1nc(N)nc(CSc2ccccc2Cl)n1 Show InChI InChI=1S/C15H19ClN6S/c1-21-6-8-22(9-7-21)15-19-13(18-14(17)20-15)10-23-12-5-3-2-4-11(12)16/h2-5H,6-10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516530 (CHEMBL4473083) Show SMILES CN1CCN(CC1)c1nc(N)nc(COc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C15H18Cl2N6O/c1-22-4-6-23(7-5-22)15-20-13(19-14(18)21-15)9-24-12-3-2-10(16)8-11(12)17/h2-3,8H,4-7,9H2,1H3,(H2,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516527 (CHEMBL4548041) Show SMILES CN1CCN(CC1)c1nc(N)nc(COc2ccccc2Cl)n1 Show InChI InChI=1S/C15H19ClN6O/c1-21-6-8-22(9-7-21)15-19-13(18-14(17)20-15)10-23-12-5-3-2-4-11(12)16/h2-5H,6-10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50492991 (CHEMBL1081718) Show SMILES CCC(C)CCNC(=O)OCCCc1c[nH]cn1 Show InChI InChI=1S/C13H23N3O2/c1-3-11(2)6-7-15-13(17)18-8-4-5-12-9-14-10-16-12/h9-11H,3-8H2,1-2H3,(H,14,16)(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
United Arab Emirates University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 23: 4886-91 (2013) Article DOI: 10.1016/j.bmcl.2013.06.075 BindingDB Entry DOI: 10.7270/Q2ZC85TZ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556126 (CHEMBL4786252) Show SMILES CC1CCN(CCCCCOc2ccc3oc4ccc(Cl)cc4c(=O)c3c2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50492992 (CHEMBL1789558) Show SMILES C=CCCCNC(=O)OCCCc1c[nH]cn1 Show InChI InChI=1S/C12H19N3O2/c1-2-3-4-7-14-12(16)17-8-5-6-11-9-13-10-15-11/h2,9-10H,1,3-8H2,(H,13,15)(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
United Arab Emirates University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 23: 4886-91 (2013) Article DOI: 10.1016/j.bmcl.2013.06.075 BindingDB Entry DOI: 10.7270/Q2ZC85TZ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556120 (CHEMBL4784081) Show SMILES CC1CCCN(CCCCCOc2ccc3oc4ccc(Cl)cc4c(=O)c3c2)C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516526 (CHEMBL4524981) Show SMILES CN1CCN(CC1)c1nc(N)nc(COc2cccc(Cl)c2)n1 Show InChI InChI=1S/C15H19ClN6O/c1-21-5-7-22(8-6-21)15-19-13(18-14(17)20-15)10-23-12-4-2-3-11(16)9-12/h2-4,9H,5-8,10H2,1H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022 BindingDB Entry DOI: 10.7270/Q22F7RSS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556114 (CHEMBL4798732) Show SMILES Clc1ccc2oc3ccc(OCCCCCN4CCCCC4)cc3c(=O)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556118 (CHEMBL4759463) Show SMILES CC1CCCN(CCCCCOc2ccc3oc4ccccc4c(=O)c3c2)C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50252361 (CHEMBL4068577) Show SMILES COc1cccc(Cc2nc(N)nc(n2)N2CCN(C)CC2)c1 Show InChI InChI=1S/C16H22N6O/c1-21-6-8-22(9-7-21)16-19-14(18-15(17)20-16)11-12-4-3-5-13(10-12)23-2/h3-5,10H,6-9,11H2,1-2H3,(H2,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HeLa cells				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50537206 (CHEMBL4483783) Show SMILES CN1CCN(CC1)c1nc(N)nc(CC2CCCCC2)n1 Show InChI InChI=1S/C15H26N6/c1-20-7-9-21(10-8-20)15-18-13(17-14(16)19-15)11-12-5-3-2-4-6-12/h12H,2-11H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from recombinant human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2/Gbeta1gamma2				Bioorg Med Chem 27: 1254-1262 (2019) Article DOI: 10.1016/j.bmc.2019.02.020 BindingDB Entry DOI: 10.7270/Q2C250Z5
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50556130 (CHEMBL4797355) Show SMILES O=c1c2ccccc2oc2ccc(OCCCCCN3CCCCCC3)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cells by microbeta scintillation analysi...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112743 BindingDB Entry DOI: 10.7270/Q2P272S9
					More data for this Ligand-Target Pair

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