| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 5 |
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| Ligand | BDBM50468153 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1798195 (CHEMBL4270312) |
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| IC50 | 0.600000±n/a nM |
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| Citation |  Liu, W; Hussain, Z; Zang, Y; Sweis, RF; Romero, FA; Finke, PE; Moningka, R; Bao, J; Plotkin, MA; Shang, J; Dingley, KH; Salituro, G; Murphy, BA; Howard, AD; Ujjainwalla, F; Wood, HB; Duffy, JL Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists. ACS Med Chem Lett9:1088-1093 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 5 |
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| Name: | Somatostatin receptor type 5 |
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| Synonyms: | SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5) |
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| Type: | Enzyme |
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| Mol. Mass.: | 39218.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35346 |
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| Residue: | 364 |
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| Sequence: | MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL
VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG
VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV
QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR
RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN
PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ
TSKL
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| BDBM50468153 |
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| n/a |
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| Name | BDBM50468153 |
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| Synonyms: | CHEMBL4279392 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N2O4S |
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| Mol. Mass. | 466.592 |
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| SMILES | CC1(C)CCSc2ccc(CN3CCC4(CN(C(=O)O4)c4ccc(cc4)C(O)=O)CC3)cc12 |
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| Structure | 
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