| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 5 |
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| Ligand | BDBM123216 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1798207 (CHEMBL4270324) |
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| IC50 | 0.300000±n/a nM |
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| Citation |  Liu, W; Hussain, Z; Zang, Y; Sweis, RF; Romero, FA; Finke, PE; Moningka, R; Bao, J; Plotkin, MA; Shang, J; Dingley, KH; Salituro, G; Murphy, BA; Howard, AD; Ujjainwalla, F; Wood, HB; Duffy, JL Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists. ACS Med Chem Lett9:1088-1093 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 5 |
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| Name: | Somatostatin receptor type 5 |
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| Synonyms: | SS-5-R | SS5-R | SS5R | SSR5_MOUSE | Smstr5 | Somatostatin receptor | Somatostatin receptor 5 | Somatostatin receptor type 5 | Sstr5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40022.97 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_833921 |
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| Residue: | 362 |
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| Sequence: | MEPLSLTSTPSWNASAASSSSHNWSLVDPVSPMGARAVLVPVLYLLVCTVGLGGNTLVIY
VVLRYAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVSYWPFGSFLCRLVMTLDGINQ
FTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKLASAAVWVFSLLMSLPLLVFADVQEG
WGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRRR
SERKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCANP
LLYGFLSDNFRQSFRKALCLRRGYGVEDADAIEPRPDKSGRPQTTLPTRSCEANGLMQTS
RL
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| BDBM123216 |
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| n/a |
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| Name | BDBM123216 |
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| Synonyms: | US8742110, 3-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H33FN2O6 |
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| Mol. Mass. | 548.6019 |
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| SMILES | CCOc1cc(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc(OCC)c1-c1ccc(F)cc1 |
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| Structure | 
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