| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50485786 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_858545 (CHEMBL2169549) |
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| Ki | 700±n/a nM |
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| Citation |  Dufau, L; Marques Ressurreição, AS; Fanelli, R; Kihal, N; Vidu, A; Milcent, T; Soulier, JL; Rodrigo, J; Desvergne, A; Leblanc, K; Bernadat, G; Crousse, B; Reboud-Ravaux, M; Ongeri, S Carbonylhydrazide-based molecular tongs inhibit wild-type and mutated HIV-1 protease dimerization. J Med Chem55:6762-75 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50485786 |
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| n/a |
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| Name | BDBM50485786 |
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| Synonyms: | CHEMBL2164074 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H48N12O10 |
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| Mol. Mass. | 760.7979 |
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| SMILES | CC(C)[C@H](NC(=O)NNC(=O)NNC(=O)CCCOc1ccc2ccc(OCCCC(=O)NNC(=O)NNC(=O)N[C@@H](C(C)C)C(N)=O)cc2c1)C(N)=O |r| |
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| Structure | 
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