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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 1A | ||
| Ligand | BDBM50063282 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1451 (CHEMBL616575) | ||
| Ki | 160±n/a nM | ||
| Citation |  Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Aminopyrimidines with high affinity for both serotonin and dopamine receptors. J Med Chem41:760-71 (1998) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 1A | |||
| Name: | 5-hydroxytryptamine receptor 1A | ||
| Synonyms: | 5-HT-1A | 5-HT1 | 5-HT1A | 5-Hydroxytryptamine receptor 1A (5-HT1A) | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_RAT | 5ht1a | G-21 | Htr1a | Serotonin 1 (5-HT1) receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 | Serotonin receptor 1A | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 46445.29 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | Binding assays were performed using rat hippocampal membranes. | ||
| Residue: | 422 | ||
| Sequence: |
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| BDBM50063282 | |||
| n/a | |||
| Name | BDBM50063282 | ||
| Synonyms: | CHEMBL2110308 | {4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H27N5 | ||
| Mol. Mass. | 337.4619 | ||
| SMILES | C1CC(CCC1Nc1ncccn1)N1CCN(CC1)c1ccccc1 |(8.5,-10.43,;10.04,-10.36,;10.74,-8.99,;9.9,-7.69,;8.36,-7.77,;7.66,-9.13,;6.12,-9.2,;5.28,-7.92,;3.77,-7.99,;2.93,-6.71,;3.63,-5.33,;5.17,-5.26,;6.01,-6.54,;12.28,-8.9,;13.12,-10.21,;14.66,-10.13,;15.34,-8.75,;14.5,-7.45,;12.98,-7.54,;16.88,-8.67,;17.72,-9.95,;19.24,-9.86,;19.94,-8.5,;19.09,-7.21,;17.56,-7.31,)| | ||
| Structure | 
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