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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(3) dopamine receptor | ||
| Ligand | BDBM50063296 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_62432 (CHEMBL674835) | ||
| Ki | 13.7±n/a nM | ||
| Citation |  Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Aminopyrimidines with high affinity for both serotonin and dopamine receptors. J Med Chem41:760-71 (1998) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(3) dopamine receptor | |||
| Name: | D(3) dopamine receptor | ||
| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 | ||
| Type: | n/a | ||
| Mol. Mass.: | 44243.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 400 | ||
| Sequence: |
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| BDBM50063296 | |||
| n/a | |||
| Name | BDBM50063296 | ||
| Synonyms: | CHEMBL165679 | {4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-pyrimidin-2-yl-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H31N5 | ||
| Mol. Mass. | 365.515 | ||
| SMILES | C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.21,-6.02,;10.05,-7.32,;11.59,-7.24,;12.43,-8.53,;13.97,-8.45,;14.66,-7.08,;13.82,-5.79,;12.29,-5.86,;16.2,-6.99,;17.03,-8.27,;18.56,-8.18,;19.26,-6.83,;18.41,-5.53,;16.88,-5.63,;7.68,-6.1,;6.84,-4.81,;5.31,-4.88,;4.6,-6.26,;5.44,-7.54,;6.98,-7.47,;3.06,-6.33,;2.22,-5.03,;.7,-5.11,;-.14,-3.81,;.56,-2.44,;2.1,-2.37,;2.94,-3.67,)| | ||
| Structure | 
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