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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM50063298 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_60370 (CHEMBL672206) | ||
| Ki | 11±n/a nM | ||
| Citation |  Wustrow, D; Belliotti, T; Glase, S; Kesten, SR; Johnson, D; Colbry, N; Rubin, R; Blackburn, A; Akunne, H; Corbin, A; Davis, MD; Georgic, L; Whetzel, S; Zoski, K; Heffner, T; Pugsley, T; Wise, L Aminopyrimidines with high affinity for both serotonin and dopamine receptors. J Med Chem41:760-71 (1998) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
| Type: | Cell-surface receptors | ||
| Mol. Mass.: | 50647.10 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14416 | ||
| Residue: | 443 | ||
| Sequence: |
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| BDBM50063298 | |||
| n/a | |||
| Name | BDBM50063298 | ||
| Synonyms: | (4-{2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine | CHEMBL350352 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H29Cl2N5 | ||
| Mol. Mass. | 434.405 | ||
| SMILES | Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)Nc3ncccn3)CC2)c1Cl |wU:15.18,wD:12.11,(19.11,-4.18,;18.42,-5.56,;19.28,-6.84,;18.57,-8.23,;17.04,-8.3,;16.21,-7.01,;14.66,-7.1,;13.82,-5.81,;12.29,-5.88,;11.59,-7.27,;10.04,-7.34,;9.2,-6.05,;7.66,-6.12,;6.82,-4.83,;5.29,-4.9,;4.57,-6.28,;5.42,-7.57,;6.96,-7.5,;3.03,-6.35,;2.19,-5.04,;.66,-5.13,;-.18,-3.82,;.52,-2.44,;2.07,-2.37,;2.91,-3.68,;12.43,-8.55,;13.98,-8.48,;16.89,-5.65,;16.04,-4.36,)| | ||
| Structure | 
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