| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50106105 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_153721 |
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| EC50 | 19±n/a nM |
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| Citation |  Liu, KG; Lambert, MH; Leesnitzer, LM; Oliver, W; Ott, RJ; Plunket, KD; Stuart, LW; Brown, PJ; Willson, TM; Sternbach, DD Identification of a series of PPAR gamma/delta dual agonists via solid-phase parallel synthesis. Bioorg Med Chem Lett11:2959-62 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50106105 |
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| n/a |
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| Name | BDBM50106105 |
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| Synonyms: | 2-[3-(3-{(2,4-Bis-trifluoromethyl-benzyl)-[2-(4-trifluoromethyl-phenyl)-acetyl]-amino}-propyl)-phenoxy]-2-methyl-propionic acid | CHEMBL102004 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H28F9NO4 |
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| Mol. Mass. | 649.5439 |
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| SMILES | CC(C)(Oc1cccc(CCCN(Cc2ccc(cc2C(F)(F)F)C(F)(F)F)C(=O)Cc2ccc(cc2)C(F)(F)F)c1)C(O)=O |
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| Structure | 
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