| Reaction Details |
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 | Report a problem with these data |
| Target | Glucagon receptor |
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| Ligand | BDBM50110058 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_72874 |
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| IC50 | 2700±n/a nM |
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| Citation |  Ling, A; Plewe, M; Gonzalez, J; Madsen, P; Sams, CK; Lau, J; Gregor, V; Murphy, D; Teston, K; Kuki, A; Shi, S; Truesdale, L; Kiel, D; May, J; Lakis, J; Anderes, K; Iatsimirskaia, E; Sidelmann, UG; Knudsen, LB; Brand, CL; Polinsky, A Human glucagon receptor antagonists based on alkylidene hydrazides. Bioorg Med Chem Lett12:663-6 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucagon receptor |
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| Name: | Glucagon receptor |
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| Synonyms: | GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54026.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47871 |
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| Residue: | 477 |
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| Sequence: | MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
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| BDBM50110058 |
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| n/a |
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| Name | BDBM50110058 |
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| Synonyms: | 3,4-Dihydroxy-benzoic acid [1-[4-(4-isopropyl-benzyloxy)-3,5-dimethoxy-phenyl]-meth-(E)-ylidene]-hydrazide | CHEMBL158556 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28N2O6 |
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| Mol. Mass. | 464.5103 |
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| SMILES | COc1cc(\C=N\NC(=O)c2ccc(O)c(O)c2)cc(OC)c1OCc1ccc(cc1)C(C)C |
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| Structure | 
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