| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Envelope glycoprotein gp160 |
|---|
| Ligand | BDBM50568663 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2106390 (CHEMBL4815065) |
|---|
| IC50 | 230±n/a nM |
|---|
| Citation |  Kobayakawa, T; Tsuji, K; Konno, K; Himeno, A; Masuda, A; Yang, T; Takahashi, K; Ishida, Y; Ohashi, N; Kuwata, T; Matsumoto, K; Yoshimura, K; Sakawaki, H; Miura, T; Harada, S; Matsushita, S; Tamamura, H Hybrids of Small-Molecule CD4 Mimics with Polyethylene Glycol Units as HIV Entry Inhibitors. J Med Chem64:1481-1496 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Envelope glycoprotein gp160 |
|---|
| Name: | Envelope glycoprotein gp160 |
|---|
| Synonyms: | envelope glycoprotein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 91798.58 |
|---|
| Organism: | Human immunodeficiency virus 1 |
|---|
| Description: | gi_45357394 |
|---|
| Residue: | 814 |
|---|
| Sequence: | MRVKGIRRNYQHLWRWGTMLLGMLMICSAKEQLWVTAYYGVPVWKEATTTLFCASDAKAY
DTEVHNVWATHACVPTDPNPREVVMGNVTEEFNIWNNSMVEQMHEDIISLWDESLKPCVK
LTPLCVTFNCTNYNGTRNGTTTEPPEVKNCTTKETGIKNCSFNIATSGVEDRFKKEYALL
YTADIVQIDNSSINYTLIGCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGK
GPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEVVIRSDNFSDNAKTIIVQLKDPVVINCT
RPNNNTRKGIRIGPGRTFYTTERIIGDIRQAHCNISRTQWNNTLRLIAAKLKKQFNNKTI
IFRNSSGGDPEIVMHSFNCGGEFFYCNTTQLFNSTWVHNNTWVHNNTGNDTEEGTITLPC
RIKQIINMWQEVGKAMYAPPIKGQIRCSSNITGLILTRDGGNTSSNNETFRPGGGDMRDN
WRSELYKYKVVKIEPLGVAPTKARRRVVQREKRAVGMLGAMFLGFLGAAGSTMGAASLAL
TVQARQVVSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLGDQQLLGIWG
CSGKLICTTAVPWNDSWSNKSLKYIWDNMTWMQWEKEIDIHVDTIYQLLEASQYQQEKNE
KDLLELDKWESLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRQGYSPLSL
QTRLPTQRGPDRPEGIEEEGGERQRHIRSISEWILNNYPGRPAEPVPLQLPPLERLTLDC
NEDCGTSGTQGVGSPQVFVESPPVLESGTKEECC
|
|
|
|---|
| BDBM50568663 |
|---|
| n/a |
|---|
| Name | BDBM50568663 |
|---|
| Synonyms: | CHEMBL4859187 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H48ClN11O4 |
|---|
| Mol. Mass. | 662.226 |
|---|
| SMILES | NC(=N)NCC(=O)NCCCC[C@H](NC(N)=N)C(=O)NCCN1CCC(CC11CCCCC1)NC(=O)C(=O)Nc1ccc(Cl)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
