| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
|---|
| Ligand | BDBM50156272 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_310533 (CHEMBL834428) |
|---|
| EC50 | 0.940000±n/a nM |
|---|
| Citation |  Sawa, M; Tateishi, H; Mizuno, K; Harada, H; Oue, M; Tsujiuchi, H; Furutani, Y; Kato, S Tryptamine-based human beta3-adrenergic receptor agonists. Part 2: SAR of the methylene derivatives. Bioorg Med Chem Lett14:5963-6 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-3 adrenergic receptor |
|---|
| Name: | Beta-3 adrenergic receptor |
|---|
| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 43534.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 408 |
|---|
| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
|
|
|
|---|
| BDBM50156272 |
|---|
| n/a |
|---|
| Name | BDBM50156272 |
|---|
| Synonyms: | CHEMBL365833 | N-(3-{(R)-1-Hydroxy-2-[2-(7-methanesulfonyl-1H-indol-3-yl)-ethylamino]-ethyl}-phenyl)-3-methoxy-benzenesulfonamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H29N3O6S2 |
|---|
| Mol. Mass. | 543.655 |
|---|
| SMILES | COc1cccc(c1)S(=O)(=O)Nc1cccc(c1)[C@@H](O)CNCCc1c[nH]c2c(cccc12)S(C)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
