| Reaction Details |
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 | Report a problem with these data |
| Target | Matrix metalloproteinase-17 |
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| Ligand | BDBM50234334 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_507879 (CHEMBL952576) |
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| IC50 | >100000±n/a nM |
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| Citation |  Johnson, AR; Pavlovsky, AG; Ortwine, DF; Prior, F; Man, CF; Bornemeier, DA; Banotai, CA; Mueller, WT; McConnell, P; Yan, C; Baragi, V; Lesch, C; Roark, WH; Wilson, M; Datta, K; Guzman, R; Han, HK; Dyer, RD Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects. J Biol Chem282:27781-91 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrix metalloproteinase-17 |
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| Name: | Matrix metalloproteinase-17 |
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| Synonyms: | MMP-17 | MMP17 | MMP17_HUMAN | MT-MMP 4 | MT4-MMP | MT4MMP | MTMMP4 | Matrix metalloproteinase 17 | Matrix metalloproteinase-17 | Membrane-type matrix metalloproteinase 4 | Membrane-type-4 matrix metalloproteinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66652.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1433225 |
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| Residue: | 603 |
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| Sequence: | MRRRAARGPGPPPPGPGLSRLPLPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFG
YLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQ
ARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAG
SAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGM
DLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESV
SPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRD
RHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRP
VSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLD
DAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQADGSVAAGVDAAE
GPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPLVAATMLLLLPPLSPGALWTAAQA
LTL
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| BDBM50234334 |
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| n/a |
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| Name | BDBM50234334 |
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| Synonyms: | BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE | CHEMBL409536 | benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[3,2-c]pyrimidine-2-carboxylate | benzyl 6-benzyl-5,7-dioxo-6,7-dihydro-5H-thiazolo[3,2-f]pyrimidine-2-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16N2O4S |
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| Mol. Mass. | 392.428 |
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| SMILES | O=C(OCc1ccccc1)c1cn2c(cc(=O)n(Cc3ccccc3)c2=O)s1 |
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| Structure | 
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