| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50257254 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_562738 (CHEMBL1022410) |
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| EC50 | >10000±n/a nM |
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| Citation |  Lin, CH; Peng, YH; Coumar, MS; Chittimalla, SK; Liao, CC; Lyn, PC; Huang, CC; Lien, TW; Lin, WH; Hsu, JT; Cheng, JH; Chen, X; Wu, JS; Chao, YS; Lee, HJ; Juo, CG; Wu, SY; Hsieh, HP Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists. J Med Chem52:2618-22 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50257254 |
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| n/a |
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| Name | BDBM50257254 |
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| Synonyms: | 2-{1-[3-(5-Benzoyl-1-propyl-naphthalen-2-yloxy)-propyl]-1H-indol-5-yloxy}-2-methyl-propionicacid | CHEMBL454508 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H35NO5 |
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| Mol. Mass. | 549.6561 |
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| SMILES | CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2c(cccc12)C(=O)c1ccccc1 |
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| Structure | 
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