| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50342688 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_745194 (CHEMBL1772425) |
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| EC50 | 73±n/a nM |
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| Citation |  Szewczyk, JW; Acton, J; Adams, AD; Chicchi, G; Freeman, S; Howard, AD; Huang, Y; Li, C; Meinke, PT; Mosely, R; Murphy, E; Samuel, R; Santini, C; Yang, M; Zhang, Y; Zhao, K; Wood, HB Design of potent and selective GPR119 agonists for type II diabetes. Bioorg Med Chem Lett21:2665-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | GP119_MOUSE | Gpr119 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37009.07 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1506420 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISG
LVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGL
VAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLL
FVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSP
FLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKF
FTSILLLLPARNRGPERTRESAYHIVTISHPELDG
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| BDBM50342688 |
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| n/a |
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| Name | BDBM50342688 |
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| Synonyms: | 1-(5-methylpyridin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine | CHEMBL1771090 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H31N3O2S |
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| Mol. Mass. | 413.576 |
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| SMILES | Cc1ccc(nc1)N1CCC(CC1)C1CCN(CC1)c1ccc(cc1)S(C)(=O)=O |
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| Structure | 
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