| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 2 |
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| Ligand | BDBM50352392 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_766671 (CHEMBL1827365) |
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| IC50 | 9±n/a nM |
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| Citation |  Swanson, DM; Wong, VD; Jablonowski, JA; Shah, C; Rudolph, DA; Dvorak, CA; Seierstad, M; Dvorak, LK; Morton, K; Nepomuceno, D; Atack, JR; Bonaventure, P; Lovenberg, TW; Carruthers, NI The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor. Bioorg Med Chem Lett21:5552-6 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 2 |
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| Name: | Neuropeptide Y receptor type 2 |
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| Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42734.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y2 NPY2R HUMAN::P49146 |
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| Residue: | 381 |
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| Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
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| BDBM50352392 |
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| n/a |
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| Name | BDBM50352392 |
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| Synonyms: | CHEMBL1823577 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H36FN5O2 |
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| Mol. Mass. | 565.6803 |
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| SMILES | CCN(CC)C(=O)[C@H](N1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2cccnc2)cc1F)c1ccccc1 |r| |
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| Structure | 
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