| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50009535 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_28539 |
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| IC50 | 2692±n/a nM |
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| Citation |  Francis, JE; Webb, RL; Ghai, GR; Hutchison, AJ; Moskal, MA; deJesus, R; Yokoyama, R; Rovinski, SL; Contardo, N; Dotson, R Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines. J Med Chem34:2570-9 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50009535 |
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| n/a |
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| Name | BDBM50009535 |
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| Synonyms: | (CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol | 2-[6-Amino-2-(2-cyclohex-1-enyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHEMBL314313 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N6O4 |
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| Mol. Mass. | 390.4368 |
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| SMILES | Nc1nc(NCCC2=CCCCC2)nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O |t:7| |
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| Structure | 
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