| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50001303 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_211249 |
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| IC50 | 330±n/a nM |
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| Citation |  Williams, PD; Bock, MG; Tung, RD; Garsky, VM; Perlow, DS; Erb, JM; Lundell, GF; Gould, NP; Whitter, WL; Hoffman, JB Development of a novel class of cyclic hexapeptide oxytocin antagonists based on a natural product. J Med Chem35:3905-18 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR V2 | Antidiuretic hormone receptor | Avpr2 | Renal-type arginine vasopressin receptor | V2R_RAT | VASOPRESSIN V2 | Vasopressin receptor |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 40761.85 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | n/a |
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| Residue: | 371 |
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| Sequence: | MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLG
ALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQ
RDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGP
SERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEA
PLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCAT
ASSSLMKDTPS
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| BDBM50001303 |
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| n/a |
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| Name | BDBM50001303 |
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| Synonyms: | 18-(3-Amino-propyl)-15-benzyl-3-sec-butyl-6-(1H-indol-3-ylmethyl)-16-methyl-1,4,7,13,16,19,25-heptaaza-tricyclo[19.4.0.0*9,13*]pentacos-24-ene-2,5,8,14,17,20-hexaone | CHEMBL126765 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H55N9O6 |
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| Mol. Mass. | 781.9428 |
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| SMILES | CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)N(C)C(=O)[C@H](CCCN)NC(=O)[C@H]2CCC=NN2C1=O |c:56| |
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| Structure | 
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