| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50373362 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_467786 (CHEMBL931350) |
|---|
| IC50 | 3500±n/a nM |
|---|
| Citation |  Okamoto, O; Kobayashi, K; Kawamoto, H; Ito, S; Satoh, A; Kato, T; Yamamoto, I; Mizutani, S; Hashimoto, M; Shimizu, A; Sakoh, H; Nagatomi, Y; Iwasawa, Y; Takahashi, H; Ishii, Y; Ozaki, S; Ohta, H Identification of novel benzimidazole series of potent and selective ORL1 antagonists. Bioorg Med Chem Lett18:3278-81 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44789.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35372 |
|---|
| Residue: | 400 |
|---|
| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50373362 |
|---|
| n/a |
|---|
| Name | BDBM50373362 |
|---|
| Synonyms: | CHEMBL263919 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H27ClN4OS |
|---|
| Mol. Mass. | 382.951 |
|---|
| SMILES | CCC(C)(C)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
