| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Matrilysin |
|---|
| Ligand | BDBM50264809 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_831074 (CHEMBL2065775) |
|---|
| Ki | 96000±n/a nM |
|---|
| Citation |  Lee, M; Ikejiri, M; Klimpel, D; Toth, M; Espahbodi, M; Hesek, D; Forbes, C; Kumarasiri, M; Noll, BC; Chang, M; Mobashery, S Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors. ACS Med Chem Lett3:490-495 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Matrilysin |
|---|
| Name: | Matrilysin |
|---|
| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29681.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P09237 |
|---|
| Residue: | 267 |
|---|
| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
|
|
|
|---|
| BDBM50264809 |
|---|
| n/a |
|---|
| Name | BDBM50264809 |
|---|
| Synonyms: | 2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEMBL483857 | Thiirane (deuterium), 1-d2 | Thiirane, 1 | US10357546, SB-3CT |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H14O3S2 |
|---|
| Mol. Mass. | 306.4 |
|---|
| SMILES | O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
