| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 2 |
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| Ligand | BDBM50389590 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_833913 (CHEMBL2072493) |
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| IC50 | >1000±n/a nM |
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| Citation |  Pasternak, A; Feng, Z; de Jesus, R; Ye, Z; He, S; Dobbelaar, P; Bradley, SA; Chicchi, GG; Tsao, KL; Trusca, D; Eiermann, GJ; Li, C; Feng, Y; Wu, M; Shao, Q; Zhang, BB; Nargund, R; Mills, SG; Howard, AD; Yang, L; Zhou, YP Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist. ACS Med Chem Lett3:289-293 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 2 |
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| Name: | Somatostatin receptor type 2 |
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| Synonyms: | SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41344.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30874 |
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| Residue: | 369 |
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| Sequence: | MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
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| BDBM50389590 |
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| n/a |
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| Name | BDBM50389590 |
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| Synonyms: | CHEMBL2069502 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H26N4O |
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| Mol. Mass. | 398.5001 |
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| SMILES | C1CC(CCO1)[C@H]1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r| |
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| Structure | 
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