| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM83922 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_848940 (CHEMBL2149734) |
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| IC50 | 122000±n/a nM |
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| Citation |  Park, JY; Kim, JH; Kim, YM; Jeong, HJ; Kim, DW; Park, KH; Kwon, HJ; Park, SJ; Lee, WS; Ryu, YB Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases. Bioorg Med Chem20:5928-35 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM83922 |
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| n/a |
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| Name | BDBM83922 |
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| Synonyms: | 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione | 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-10,11-dione | 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-10,11-quinone | MLS001048863 | SMR000387068 | acs.jmedchem.1c00409_ST.743 | cid_164676 | med.21724, Compound 173 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18O3 |
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| Mol. Mass. | 294.3444 |
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| SMILES | Cc1coc-2c1C(=O)C(=O)c1c3CCCC(C)(C)c3ccc-21 |
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| Structure | 
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