| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-4 |
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| Ligand | BDBM50182216 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1585709 (CHEMBL3821006) |
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| IC50 | >700000±n/a nM |
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| Citation |  Sriwilaijaroen, N; Magesh, S; Imamura, A; Ando, H; Ishida, H; Sakai, M; Ishitsubo, E; Hori, T; Moriya, S; Ishikawa, T; Kuwata, K; Odagiri, T; Tashiro, M; Hiramatsu, H; Tsukamoto, K; Miyagi, T; Tokiwa, H; Kiso, M; Suzuki, Y A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions. J Med Chem59:4563-77 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-4 |
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| Name: | Sialidase-4 |
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| Synonyms: | NEU4 | NEUR4_HUMAN | Sialidase 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51579.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960637 |
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| Residue: | 484 |
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| Sequence: | MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGT
LAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRN
AARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYR
VDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCN
ARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGP
GSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSW
TLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYS
DLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGC
CWPS
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| BDBM50182216 |
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| n/a |
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| Name | BDBM50182216 |
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| Synonyms: | CHEMBL3819510 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H30F3N5O9 |
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| Mol. Mass. | 529.4648 |
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| SMILES | OC(=O)C(F)(F)F.[H][C@]1(OC(=C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CNC(=O)CCCC |r,c:9| |
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| Structure | 
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