| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene B4 receptor 2 |
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| Ligand | BDBM50292408 |
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| Substrate/Competitor | n/a |
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| Ki | 3.48±n/a nM |
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| Comments | PDSP_1114 |
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| Citation |  Heise, CE; O'Dowd, BF; Figueroa, DJ; Sawyer, N; Nguyen, T; Im, DS; Stocco, R; Bellefeuille, JN; Abramovitz, M; Cheng, R; Williams, DL; Zeng, Z; Liu, Q; Ma, L; Clements, MK; Coulombe, N; Liu, Y; Austin, CP; George, SR; O'Neill, GP; Metters, KM; Lynch, KR; Evans, JF Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem275:30531-6 (2000) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Leukotriene B4 receptor 2 |
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| Name: | Leukotriene B4 receptor 2 |
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| Synonyms: | BLT2R | BLTR2 | LT4R2_HUMAN | LTB4 receptor JULF2 | LTB4-R 2 | LTB4-R2 | LTB4R2 | LTB4R2 protein | Leukotriene B4 | Leukotriene B4 R2 | Leukotriene B4 receptor | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | Leukotriene b1 | Seven transmembrane receptor BLTR2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37964.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Leukotriene 2 0 HUMAN::Q9NPC1 |
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| Residue: | 358 |
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| Sequence: | MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATL
VLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRC
LAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAA
HLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPY
HAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAG
PRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
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| BDBM50292408 |
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| n/a |
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| Name | BDBM50292408 |
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| Synonyms: | (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)glycine | 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoic acid | CHEMBL288943 | LTD4 | S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycine | leukotriene D4 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H40N2O6S |
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| Mol. Mass. | 496.66 |
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| SMILES | CCCCC\C=C/C\C=C/C=C/C=C/[C@@H](SC[C@H](N)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O |r| |
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| Structure | 
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