| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 2 |
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| Ligand | BDBM177694 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Assay |
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| IC50 | 157±n/a nM |
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| Citation |  Musicki, B; Aubert, J; Rossio, P; Schuppli-Nollet, M; Clary, L; Boiteau, J Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases US Patent US9120772 Publication Date 9/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 2 |
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| Name: | C-X-C chemokine receptor type 2 |
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| Synonyms: | C-X-C chemokine receptor type 2 (CXCR-2) | C-X-C chemokine receptor type 2 (CXCR2) | CD_antigen=CD182 | CDw128b | CXCR-2 | CXCR2 | CXCR2_HUMAN | Chemokine receptor type 2 (CXCR2) | GRO/MGSA receptor | High affinity interleukin-8 receptor B | IL-8 receptor type 2 | IL-8R B | IL8RB | Interleukin-8 receptor B |
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| Type: | Protein |
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| Mol. Mass.: | 40767.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25025 |
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| Residue: | 360 |
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| Sequence: | MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFL
LSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCK
VVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPV
LLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFK
AHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATE
ILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
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| BDBM177694 |
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| n/a |
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| Name | BDBM177694 |
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| Synonyms: | US9120772, 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N3O6 |
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| Mol. Mass. | 467.5143 |
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| SMILES | CN(C)C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)CCOCC3)c(=O)c2=O)c1O |
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| Structure | 
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