| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM360931 |
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| Substrate/Competitor | n/a |
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| IC50 | 0.197±n/a nM |
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| Citation |  Bennett, F; Jiang, J; Pasternak, A; Dong, S; Gu, X; Scott, JD; Tang, H; Zhao, Z; Huang, Y; Yang, D; Young, K; Xiao, L; Zhang, Z; Fu, J Metallo-beta-lactamase inhibitors US Patent US10544130 Publication Date 1/28/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29508.45 |
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| Organism: | n/a |
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| Description: | Q2QC95 |
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| Residue: | 266 |
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| Sequence: | MKTFAAYVIIACLSSTALAGSITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARAS
KEYLPASTFKIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQWERDLTLRGAIQVSAVPVF
QQIAREVGEVRMQKYLKKFSYGNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSA
SKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAWWVGWVEKETEVYFFAFNMD
IDNESKLPLRKSIPTKIMESEGIIGG
|
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|
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| BDBM360931 |
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| n/a |
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| Name | BDBM360931 |
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| Synonyms: | N1-(2-amino-2- methylpropyl)- 4-(2-aminobenzo [d]thiazol- 4-yl)-3-(1H- tetrazol-5- yl)benzene-1,2- disulfonamide | US10221163, Example 87 | US10544130, Example 87 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N9O4S3 |
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| Mol. Mass. | 523.612 |
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| SMILES | CC(C)(N)CNS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nnn[nH]2)c1S(N)(=O)=O |
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| Structure | 
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