| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM360932 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 0.230±n/a nM |
|---|
| Citation |  Bennett, F; Jiang, J; Pasternak, A; Dong, S; Gu, X; Scott, JD; Tang, H; Zhao, Z; Huang, Y; Yang, D; Young, K; Xiao, L; Zhang, Z; Fu, J Metallo-beta-lactamase inhibitors US Patent US10544130 Publication Date 1/28/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | n/a |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 29508.45 |
|---|
| Organism: | n/a |
|---|
| Description: | Q2QC95 |
|---|
| Residue: | 266 |
|---|
| Sequence: | MKTFAAYVIIACLSSTALAGSITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARAS
KEYLPASTFKIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQWERDLTLRGAIQVSAVPVF
QQIAREVGEVRMQKYLKKFSYGNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSA
SKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAWWVGWVEKETEVYFFAFNMD
IDNESKLPLRKSIPTKIMESEGIIGG
|
|
|
|---|
| BDBM360932 |
|---|
| n/a |
|---|
| Name | BDBM360932 |
|---|
| Synonyms: | 4-(2-aminobenzo [d]thiazol-4-yl)- N1-(2-azabicyclo [2.2.1]heptan- 6-yl)-3-(1H- tetrazol-5- yl)benzene-1,2- disulfonamide | US10221163, Example 88 | US10221163, Example 89 | US10544130, Example 89 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H21N9O4S3 |
|---|
| Mol. Mass. | 547.634 |
|---|
| SMILES | Nc1nc2c(cccc2s1)-c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)S(=O)(=O)NC1CC2CNC1C2 |
|---|
| Structure | 
|
|---|
Search and Browse
