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PMIDDataArticle TitleCitationOrganizationData Download
34665619 189 Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity.BDB J Med Chem (2021) TBA 2D 3D TSV
34651447 87 A patent review on SARS coronavirus main protease (3CLpro) inhibitors.BDB ChemMedChem (2021) Experimental Drug Development Centre 2D 3D TSV
34528437 44 Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies.BDB J Med Chem 64: 14702-14714 (2021) Purdue University 2D 3D TSV
34426525 6 DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 MBDB Proc Natl Acad Sci U S A 118: (2021) Baylor College of Medicine 2D 3D TSV
34414360 60 Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir.BDB ACS Pharmacol Transl Sci 4: 1408-1421 (2021) The University of Arizona 2D 3D TSV
34408808 72 Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency.BDB ACS Med Chem Lett 12: 1325-1332 (2021) Yale University 2D 3D TSV
34347470 98 Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CLBDB J Med Chem 64: (2021) Cleveland Clinic 2D 3D TSV
34271072 34 A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors.BDB Bioorg Med Chem Lett 48: 128263 (2021) A*STAR 2D 3D TSV
34242027 24 Peptidomimetic ?-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and BDB J Med Chem (2021) University of Alberta 2D 3D TSV
34213885 38 Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease.BDB J Med Chem 64: 10047-10058 (2021) Wichita State University 2D 3D TSV

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