41 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27287367	36	Evaluation of bisbenzamidines as inhibitors for matriptase-2.	University of Bonn
26114810	8	Synthesis of 3,4-diaminobenzoyl derivatives as factor Xa inhibitors.	Southeast University
25650311	76	Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3.	Chang Gung University
25268757	16	How aß-D-glucoside side chain enhances binding affinity to thrombin of inhibitors bearing 2-chlorothiophene as P1 moiety: crystallography, fragment deconstruction study, and evaluation of antithrombotic properties.	Consiglio Nazionale Delle Ricerche
1271404	55	Novel bis(benzamidino) compounds with an aromatic central link. Inhibitors of thrombin, pancreatic kallikrein, trypsin, and complement.	TBA
671460	122	Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases.	TBA
660589	3	Inactivation of trypsin-like proteases by sulfonylation. Variation of positively charged group and inhibitor length.	TBA
24102612	105	Synthesis and biological evaluation of direct thrombin inhibitors bearing 4-(piperidin-1-yl)pyridine at the P1 position with potent anticoagulant activity.	University of Bari &Quot;Aldo Moro&Quot
7401110	109	Thrombin inhibitors. 2. Amide derivatives of N alpha-substituted L-arginine.	TBA
7401109	32	Thrombin inhibitors. 1. Ester derivatives of N alpha-(arylsulfonyl)-L-arginine.	TBA
22950366	6	Thrombin inhibitors from the freshwater cyanobacterium Anabaena compacta.	Hokkaido University
20561792	4	Development of tryptase inhibitors derived from thalidomide.	The University of Tokyo
12036355	36	Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 1. Models without explicit constrained water.	University of Parma
11297451	21	Estimation of binding affinities for selective thrombin inhibitors via Monte Carlo simulations.	Yale University
10956211	14	GRID/CPCA: a new computational tool to design selective ligands.	Boehringer Ingelheim Pharma
10579821	51	Design and synthesis of thrombin inhibitors: analogues of MD-805 with reduced stereogenicity and improved potency.	Novartis Horsham Research Centre
9301673	234	Synthesis and structure-activity relationships of potent thrombin inhibitors: piperazides of 3-amidinophenylalanine.	Klinikum Der Friedrich-Schiller-Universit£T Jena
8478905	53	Inhibition studies of some serine and thiol proteinases by new leupeptin analogues.	University of Arkansas
3625715	21	Anticoagulant peptides: nature of the interaction of the C-terminal region of hirudin with a noncatalytic binding site on thrombin.	TBA
19193009	25	Fluorinated benzyloxyphenyl piperidine-4-carboxamides with dual function against thrombosis: inhibitors of factor Xa and platelet aggregation.	University of Bari
	19	Rational design of selective thrombin inhibitors	TBA
	61	(N-acyl-N-alkyl)glycyl borolysine analogs: A new class of potent thrombin inhibitors	TBA
	13	Characterization of LY806303 as a potent and selective inhibitor of thrombin	TBA
9834152	29	Effects of tannins from Geum japonicum on the catalytic activity of thrombin and factor Xa of blood coagulation cascade.	National University of Singapore
11549459	5	Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase.	National Cancer Institute-Frederick
27280436	304	Optimization of Cyclic Plasmin Inhibitors: From Benzamidines to Benzylamines.	Philipps University Marburg
9876114	111	Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase.	Institut FüR Biochemie
9871573	15	Discovery of LB30057, a benzamidrazone-based selective oral thrombin inhibitor.	Biotech Research Institute
9784099	84	Design of benzamidine-type inhibitors of factor Xa.	Institut FüR Biochemie
7473571	90	Structure-activity study of tripeptide thrombin inhibitors using alpha-alkyl amino acids and other conformationally constrained amino acid substitutions.	Eli Lilly
6219223	94	Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin.	TBA
9986717	264	Three-dimensional quantitative structure-activity relationship analyses using comparative molecular field analysis and comparative molecular similarity indices analysis to elucidate selectivity differences of inhibitors binding to trypsin, thrombin, and factor Xa.	University of Marburg
29072911	16	Design of Small-Molecule Active-Site Inhibitors of the S1A Family Proteases as Procoagulant and Anticoagulant Drugs.	University of Nottingham
28850227	85	Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.	St. John'S University