The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27522507 |
14 |
Synthetic, enzyme kinetic, and protein crystallographic studies of C-ß-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase. |
University of Thessaly |
27624527 |
19 |
Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors. |
Egypt National Research Centre |
26708111 |
41 |
Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition. |
Universit£ |
25092521 |
50 |
Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-ß-d-glucopyranosylamines. |
University of Thessaly |
23395662 |
2 |
Synthesis of tartaric acid analogues of FR258900 and their evaluation as glycogen phosphorylase inhibitors. |
University of Debrecen |
22229710 |
18 |
Binding evaluation of fragment-based scaffolds for probing allosteric enzymes. |
Universit£ |
18595718 |
51 |
In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. |
Hokuriku University |
15214781 |
30 |
Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site. |
Novo Nordisk |
11495595 |
24 |
Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of d-gluco- and d-xylopyranosylidene-spiro-(thio)hydantoins and N-(d-glucopyranosyl) amides. |
University of Debrecen |
21788139 |
43 |
Ligand-based modelling followed by synthetic exploration unveil novel glycogen phosphorylase inhibitory leads. |
Applied Science University |
20493691 |
19 |
Discovery of a series of indan carboxylic acid glycogen phosphorylase inhibitors. |
Astrazeneca |
19095443 |
66 |
Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues. |
Glaxosmithkline |
19095442 |
70 |
Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups. |
Glaxosmithkline |
18723356 |
18 |
Synthesis and pharmacological evaluation of bis-3-(3,4-dichlorophenyl)acrylamide derivatives as glycogen phosphorylase inhibitors. |
Astellas Pharma |
18554908 |
63 |
Amino acid anthranilamide derivatives as a new class of glycogen phosphorylase inhibitors. |
Glaxosmithkline |
17451960 |
5 |
Synthesis and glycogen phosphorylase inhibitor activity of 2,3-dihydrobenzo[1,4]dioxin derivatives. |
University of Debrecen |
16970395 |
14 |
Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition. |
The National Hellenic Research Foundation |
16945526 |
19 |
Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies. |
Astrazeneca |
16942879 |
24 |
Synthesis and structure-activity relationships of 3-phenyl-2-propenamides as inhibitors of glycogen phosphorylase a. |
Glaxosmithkline |
16190745 |
85 |
Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. |
Sanofi-Aventis Deutschland |
15603973 |
88 |
5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization. |
Pfizer |
14643331 |
71 |
Novel 3,4-dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a. |
Merck Research Laboratories |
14592521 |
50 |
A new class of glycogen phosphorylase inhibitors. |
Merck Research Laboratories |
14505637 |
40 |
Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors. |
Merck Research Laboratories |
31767404 |
9 |
The architecture of hydrogen and sulfur ?-hole interactions explain differences in the inhibitory potency of C-?-d-glucopyranosyl thiazoles, imidazoles and an N-?-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. |
University of Thessaly |
9685232 |
26 |
Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase. |
Pfizer |
29453094 |
19 |
A multidisciplinary study of 3-(?-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors. |
University of Debrecen |
28925695 |
25 |
Nanomolar Inhibitors of Glycogen Phosphorylase Based on?-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. |
University of Debrecen |
11961053 |
26 |
Biochemical and behavioral characterization of novel methylphenidate analogs. |
Mercer University |
11752130 |
5 |
The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin. |
Merck Research Laboratories |
19101474 |
3 |
Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis. |
University of Toronto |