The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 27131064 |
22 |
Synthesis and bioevaluation of novel benzodipyranone derivatives as P-glycoprotein inhibitors for multidrug resistance reversal agents. |
China Medical University |
| 27262425 |
14 |
Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport. |
Kyoto University |
| 27100033 |
40 |
The combination of quinazoline and chalcone moieties leads to novel potent heterodimeric modulators of breast cancer resistance protein (BCRP/ABCG2). |
University Of Bonn |
| 26836364 |
30 |
Optimization by Molecular Fine Tuning of Dihydro-ß-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance. |
Instituto Universitario De Bio-Org£Nica&Quot;Antonio Gonz£Lez&Quot |
| 26774038 |
67 |
Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization. |
University Of Regensburg |
| 26123642 |
38 |
The interaction of 4-thiazolidinone derivatives containing indolin-2-one moiety with P-glycoprotein studied using K562 cell lines. |
The First Affiliated Hospital Of Dalian Medical University |
| 26233798 |
11 |
Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitors. |
Ocean University Of China |
| 26048803 |
3 |
Discovery of substituted 1,4-dihydroquinolines as novel promising class of P-glycoprotein inhibitors: First structure-activity relationships and bioanalytical studies. |
Martin-Luther-University Halle-Wittenberg |
| 25985195 |
94 |
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives. |
The Hong Kong Polytechnic University |
| 25695368 |
4 |
Restoration of Chemosensitivity in P-Glycoprotein-Dependent Multidrug-Resistant Cells by Dihydro-ß-agarofuran Sesquiterpenes from Celastrus vulcanicola. |
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Iubo-Ag) |
| 23132334 |
28 |
In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor. |
Glaxosmithkline |
| 25855895 |
23 |
HM30181 Derivatives as Novel Potent and Selective Inhibitors of the Breast Cancer Resistance Protein (BCRP/ABCG2). |
University Of Bonn |
| 25093931 |
44 |
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding. |
Universit£ |
| 25499431 |
4 |
Investigating the binding interactions of the anti-Alzheimer's drug donepezil with CYP3A4 and P-glycoprotein. |
University Of Waterloo |
| 25462276 |
39 |
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate P-glycoprotein (P-gp) activity froms2 receptor affinity in mixed P-gp/s2 receptor agents. |
Universit£ |
| 25379609 |
24 |
SAR studies on tetrahydroisoquinoline derivatives: the role of flexibility and bioisosterism to raise potency and selectivity toward P-glycoprotein. |
Universit£ |
| 25310383 |
50 |
Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition. |
Novartis Institutes For Biomedical Research |
| 24952376 |
2 |
4,5-Di-substituted benzyl-imidazol-2-substituted amines as the structure template for the design and synthesis of reversal agents against P-gp-mediated multidrug resistance breast cancer cells. |
Ocean University Of China |
| 24773054 |
11 |
Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole amino acid. |
St. John'S University |
| 24613626 |
21 |
Synthesis, biological evaluation and 3D-QSAR studies of new chalcone derivatives as inhibitors of human P-glycoprotein. |
Medical University Vienna |
| 24607999 |
16 |
SAR study on arylmethyloxyphenyl scaffold: looking for a P-gp nanomolar affinity. |
Universit£ |
| 24184213 |
71 |
Investigation of quinazolines as inhibitors of breast cancer resistance protein (ABCG2). |
University Of Bonn |
| 24161678 |
9 |
Development of 3,4-dihydroisoquinolin-1(2H)-one derivatives for the Positron Emission Tomography (PET) imaging ofs2 receptors. |
Universit£ |
| 23332369 |
5 |
Synthesis of N(4)-(substituted phenyl)-N(4)-alkyl/desalkyl-9H-pyrimido[4,5-b]indole-2,4-diamines and identification of new microtubule disrupting compounds that are effective against multidrug resistant cells. |
Duquesne University |
| 23374872 |
27 |
Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp. |
Universit£ |
| 23347803 |
29 |
Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters. |
Universit£ |
| 24900683 |
26 |
Benzanilide-Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-Type ABCG2 Modulators. |
University Of Regensburg |
| 21723648 |
41 |
Docking and 3D-QSAR (quantitative structure activity relationship) studies of flavones, the potent inhibitors of p-glycoprotein targeting the nucleotide binding domain. |
Chosun University |
| 15331656 |
2 |
Intrinsic and acquired forms of resistance against the anticancer ruthenium compound KP1019 [indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A). |
Institute Of Cancer Research |
| 15359574 |
1 |
Transport characteristics of fexofenadine in the Caco-2 cell model. |
Uppsala University |
| 9914792 |
3 |
Inhibitory effects of a cyclosporin derivative, SDZ PSC 833, on transport of doxorubicin and vinblastine via human P-glycoprotein. |
Kobe University |
| 11145223 |
7 |
Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison with the effects on CYP3A4. |
Kanazawa University |
| 11231118 |
8 |
Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport. |
Kanazawa University |
| 7562598 |
1 |
Cepharanthin, a multidrug resistant modifier, is a substrate for P-glycoprotein. |
Kyoto University Hospital |
| 8862725 |
8 |
Ranking of P-glycoprotein substrates and inhibitors by a calcein-AM fluorometry screening assay. |
Strasbourg 1 University |
| 12134945 |
9 |
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa? |
The University Of Kansas |
| 11474784 |
6 |
HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein. |
Schering-Plough Research Institute |
| 11743742 |
6 |
Quantitative distinctions of active site molecular recognition by P-glycoprotein and cytochrome P450 3A4. |
Schering-Plough Research Institute |
| 11606389 |
1 |
The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein. |
Schering-Plough Research Institute |
| 11027568 |
1 |
Cholesterol interaction with the daunorubicin binding site of P-glycoprotein. |
Schering-Plough Research Institute |
| 11452702 |
1 |
P-glycoprotein interactions of nefazodone and trazodone in cell culture. |
Tufts University School Of Medicine |
| 11408360 |
1 |
Methadone inhibits rhodamine123 transport in Caco-2 cells. |
Tufts University School Of Medicine |
| 11454724 |
3 |
Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein. |
Schering-Plough Research Institute |
| 11716514 |
103 |
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors. |
Schering-Plough Research Institute |
| 11751127 |
2 |
Interaction of common azole antifungals with P glycoprotein. |
Schering-Plough Research Institute |
| 10820137 |
13 |
Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes. |
Vanderbilt University School Of Medicine |
| 12700464 |
1 |
Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein. |
Tufts University School Of Medicine |
| 10901697 |
1 |
Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro. |
Vanderbilt University School Of Medicine |
| 11964599 |
4 |
Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein. |
Vanderbilt University |
| 11770010 |
3 |
Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein. |
Institute Of Clinical Pharmacology |
| 10773005 |
2 |
Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein. |
Dr. Margarete Fischer-Bosch-Institute Of Clinical Pharmacology |
| 10729360 |
1 |
Inhibition of the P-glycoprotein- and multidrug resistance protein-mediated efflux of anthracyclines and calceinacetoxymethyl ester by PAK-104P. |
Universit£ |
| 15240100 |
12 |
Reversal of P-glycoprotein-mediated MDR by 5,7,3',4',5'-pentamethoxyflavone and SAR. |
Chosun University |
| 15616150 |
14 |
Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1. |
Pfizer |
| 12569305 |
12 |
Differential effects of the optical isomers of KR30031 on cardiotoxicity and on multidrug resistance reversal activity. |
Korea Research Institute Of Chemical Technology |
| 14755051 |
1 |
Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine. |
Washington University |
| 10411602 |
2 |
Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities. |
Eli Lilly |
| 17890094 |
35 |
New functional assay of P-glycoprotein activity using Hoechst 33342. |
University Of Bonn |
| 16722621 |
3 |
New potent P-glycoprotein inhibitors carrying a polycyclic scaffold. |
University Of Bologna |
| 15481991 |
2 |
Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. |
Yale University |
| 11784143 |
4 |
C-7 analogues of progesterone as potent inhibitors of the P-glycoprotein efflux pump. |
Georgetown University School Of Medicine |
| 10386932 |
56 |
Synthesis and evaluation of hapalosin and analogs as MDR-reversing agents. |
Eisai Research Institute |
| 22727780 |
17 |
Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1). |
The State University Of New York |
| 22541068 |
73 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. |
Uppsala University |
| 12604693 |
1 |
Pharmacokinetics and interactions of a novel antagonist of chemokine receptor 5 (CCR5) with ritonavir in rats and monkeys: role of CYP3A and P-glycoprotein. |
Merck Research Laboratories |
| 11961113 |
36 |
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. |
Eli Lilly |
| 9751076 |
2 |
Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein. |
Eli Lilly |
| 12130727 |
2 |
Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. |
Dr. Margarete Fischer-Bosch-Institute Of Clinical Pharmacology |
| 10198227 |
3 |
PSC833, cyclosporin A, and dexniguldipine effects on cellular calcein retention and inhibition of the multidrug resistance pump in human leukemic lymphoblasts. |
University Of Tennessee Medical Center |
| 19721074 |
1 |
Nonclinical pharmacokinetics of oseltamivir and oseltamivir carboxylate in the central nervous system. |
F. Hoffmann-La Roche |
| 24900226 |
3 |
From taxuspine x to structurally simplified taxanes with remarkable p-glycoprotein inhibitory activity. |
TBA |
| 17664327 |
10 |
Effects of human immunodeficiency virus protease inhibitors on the intestinal absorption of tenofovir disoproxil fumarate in vitro. |
Gilead Sciences |
| 19170519 |
34 |
Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. |
University Of Regensburg |
| 18083034 |
70 |
Functional assay and structure-activity relationships of new third-generation P-glycoprotein inhibitors. |
University Of Bonn |
| 17936633 |
16 |
Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives. |
Universit£ |
| 18257545 |
34 |
Synthesis and biological evaluation of (hetero)arylmethyloxy- and arylmethylamine-phenyl derivatives as potent P-glycoprotein modulating agents. |
Universita Degli Studi Di Bari |
| 17352460 |
159 |
Self-organizing maps for identification of new inhibitors of P-glycoprotein. |
University Of Vienna |
| 16686543 |
44 |
Identification of a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells. |
Universit£ |
| 12699389 |
152 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. |
F. Hoffmann-La Roche |
| 12477351 |
41 |
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis). |
Bulgarian Academy Of Sciences |
| 12361387 |
59 |
Cyclosporins: structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC transporter. |
Strasbourg 1 University |
| 10891114 |
28 |
Aureobasidins: structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC-transporter. |
Strasbourg 1 University |
| 9767638 |
24 |
Substituted 4-acylpyrazoles and 4-acylpyrazolones: synthesis and multidrug resistance-modulating activity. |
University Of Vienna |
| 22112208 |
98 |
Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein. |
Universit£ |
| 21856049 |
8 |
Overcoming human P-glycoprotein-dependent multidrug resistance with novel dihydro-ß-agarofuran sesquiterpenes. |
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Iubo-Ag) |
| 21570282 |
28 |
Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). |
Universidad Nacional De Colombia |
| 21341745 |
4 |
A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields. |
University Of Perugia |
| 21189339 |
5 |
Interaction potential of etravirine with drug transporters assessed in vitro. |
University Hospital Heidelberg |
| 21354800 |
77 |
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP). |
University Of Bonn |
| 20731360 |
6 |
Potent and fully noncompetitive peptidomimetic inhibitor of multidrug resistance P-glycoprotein. |
Umr 5086 Cnrs |
| 20684594 |
71 |
Phenylsulfonylfuroxans as modulators of multidrug-resistance-associated protein-1 and P-glycoprotein. |
Universita Degli Studi Di Torino |
| 19819706 |
16 |
Antimalarial and antitrypanosomal activity of a series of amide and sulfonamide derivatives of a 2,5-diaminobenzophenone. |
Philipps-Universit£T Marburg |
| 19402665 |
29 |
Rhodamine inhibitors of P-glycoprotein: an amide/thioamide"switch" for ATPase activity. |
The State University Of New York |
| 19053888 |
114 |
2-[(3-Methoxyphenylethyl)phenoxy]-based ABCB1 inhibitors: effect of different basic side-chains on their biological properties. |
Universita Degli Studi Di Bari |
| 18954040 |
5 |
Bis-pyranobenzoquinones as a new family of reversal agents of the multidrug resistance phenotype mediated by P-glycoprotein in mammalian cells and the protozoan parasite Leishmania. |
Instituto Universitario De Bio-OrgáNica Antonio GonzáLez |
| 18524592 |
4 |
Effect of some P-glycoprotein modulators on Rhodamine-123 absorption in guinea-pig ileum. |
Università |
| 17850057 |
72 |
Biological evaluation, structure-activity relationships, and three-dimensional quantitative structure-activity relationship studies of dihydro-beta-agarofuran sesquiterpenes as modulators of P-glycoprotein-dependent multidrug resistance. |
Instituto Universitario De Bio-Organica Antonio Gonzalez |
| 17399990 |
45 |
In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity on CYP-450 (Part 2). |
Université |
| 17064079 |
22 |
Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition. |
Università |
| 16640345 |
9 |
Biological evaluation of bishydroxymethyl-substituted cage dimeric 1,4-dihydropyridines as a novel class of p-glycoprotein modulating agents in cancer cells. |
Martin-Luther-University Halle-Wittenberg |
| 16458504 |
37 |
Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: a novel agonist 5-HT1A receptor PET ligand. |
Columbia University College Of Physicians And Surgeons |
| 16392798 |
46 |
Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand. |
Columbia University College Of Physicians And Surgeons |
| 11958985 |
21 |
Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1). |
Eli Lilly |
| | 35 |
Cycloalkylpiperazines as HIV-1 Protease Inhibitors: Enhanced Oral Absorption |
Merck Research Laboratories |
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