The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
8515425 |
65 |
Potent nonpeptide angiotensin II receptor antagonists. 2. 1-(Carboxybenzyl)imidazole-5-acrylic acids. |
Smithkline Beecham Pharmaceuticals |
1875338 |
7 |
Conformationally restricted polysubstituted biphenyl derivatives with angiotensin II receptors antagonist properties. |
Searle R & D and Mcr |
1875348 |
65 |
Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives. |
E. I. Du Pont De Nemours |
1956044 |
115 |
Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype. |
Warner-Lambert |
2329554 |
20 |
Nonpeptide angiotensin II receptor antagonists: N-[(benzyloxy)benzyl]imidazoles and related compounds as potent antihypertensives. |
E. I. Du Pont De Nemours And |
2329553 |
81 |
The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives. |
E. I. Du Pont De Nemours |
2704034 |
16 |
Topographic probes of angiotensin and receptor: potent angiotensin II agonist containing diphenylalanine and long-acting antagonists containing biphenylalanine and 2-indan amino acid in position 8. |
Washington State University |
26314922 |
2 |
Imidazopyridines as a source of biological activity and their pharmacological potentials-Infrared and Raman spectroscopic evidence of their content in pharmaceuticals and plant materials. |
Wroclaw University of Economics |
20493713 |
30 |
Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. |
Uppsala University |
10821712 |
18 |
Quantized surface complementarity diversity (QSCD): a model based on small molecule-target complementarity. |
Neogenesis |
8576904 |
78 |
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy. |
Dupont Pharmaceuticals |
| 32 |
L-161,638: A potent AT2selective quinazolinone angiotensin II binding inhibitor |
TBA |
| 17 |
1,4-substituted indoles: a potent and selective class of angiostensin II receptor antagonists |
TBA |
| 24 |
The design, binding affinity prediction and synthesis of macrocyclic angiotensin II AT1 and AT2 receptor antagonists |
TBA |
| 10 |
L-162,389: a potent orally active angiotensin II receptor antagonist with balanced affinity to both AT1 and AT2 receptor subtypes |
TBA |
| 54 |
4,5-Dihydro-4-oxo-3H-imidazo[4,5-c]pyridines: potent arylacetic acid-derived AT1 antagonists with improved affinity for the AT2 receptor |
TBA |
| 54 |
α-Phenoxyphenylacetic acid derived angiotensin II antagonists with low nanomolar AT1/AT2 receptor subtype affinity (Part II) |
TBA |
| 19 |
2,3,6-Substituted quinazolinones as angiotensin II receptor antagonists |
TBA |
| 8 |
Substituted 1,3-benzodioxole & 1,3-benzodithiole -2- carboxylates and their tetrazole analogs with potent binding affinity to the angiotensin II AT1 receptor |
TBA |
| 56 |
Potent triazolinone-based angiotensin II receptor antagonists with equivalent affinity for both the AT1 and AT2 subtypes |
TBA |
| 134 |
Development of angiotensin II antagonists with equipotent affinity for human AT1 and AT2 receptor subtypes. |
TBA |
| 46 |
Balanced angiotensin II receptor antagonists. I. The effects of biphenyl “ortho”-substitution on AT1/AT2 affinities |
TBA |
| 10 |
Synthesis and biological evaluation of the potent isoxazolidinyl angiotensin II receptor antagonist CL332,877 and its enantiomers. |
TBA |
| 34 |
6-isoxazolinyl and isoxazolidinyl substituted quinazolinones as angiotensin II receptor antagonists |
TBA |
| 54 |
A new class of balanced AT1/AT2 angiotensin II antagonists: quinazolinone AII antagonists with acylsulfonamide and sulfonylcarbamate acidic functionalities |
TBA |
| 36 |
Quinazolinone Biphenyl Acylsulfonamides: A potent new class of angiotensin-II receptor antagonists |
TBA |
| 50 |
Potent imidazole angiotensinII antagonists: acyl sulfonamides and acyl sulfamides as tetrazole replacements |
TBA |
| 8 |
Synthesis of new imidazo[1,2-b]pyridazine isosteres of potent imidazo[4,5-b]pyridine angiotensin II antagonists |
TBA |
| 24 |
Subtituted phenylthiophene benzoylsulfonamides with potent binding affinity to angiotensin II AT1 and AT2 receptors |
TBA |
| 42 |
Imidazo[4,5-b]pyridine-based AT1 / AT2 angiotensin II receptor antagonists |
TBA |
| 19 |
Triazolinones as nonpeptide angiotensin II antagonists. 2. discovery of a potent and orally active triazolinone acylsulfonamide |
TBA |
| 10 |
Angiotensin II receptor antagonists containing a phenylpyridine element. |
TBA |
| 56 |
Synthesis and structure-activity relationships of a novel series of non-peptide AT2-selective angiotensin II receptor antagonists |
TBA |
17125268 |
44 |
Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships. |
Uppsala University |
32030982 |
14 |
The Other Angiotensin II Receptor: AT |
Centre Hospitalier Universitaire Vaudois (Chuv) and University of Lausanne (Unil |
8421274 |
27 |
Nonpeptide angiotensin II antagonists: N-phenyl-1H-pyrrole derivatives are angiotensin II receptor antagonists. |
Searle |
8277506 |
58 |
Non-peptide angiotensin II receptor antagonists. 2. Design, synthesis, and biological activity of N-substituted (phenylamino)phenylacetic acids and acyl sulfonamides. |
Merck Research Laboratories |
8277505 |
58 |
Non-peptide angiotensin II receptor antagonists. 1. Design, synthesis, and biological activity of N-substituted indoles and dihydroindoles. |
Merck Research Laboratories |
8258820 |
47 |
A novel series of selective, non-peptide inhibitors of angiotensin II binding to the AT2 site. |
Dupont Pharmaceuticals |
8246245 |
26 |
(Dipropylphenoxy)phenylacetic acids: a new generation of nonpeptide angiotensin II receptor antagonists. |
Merck Research Laboratories |
8230109 |
18 |
A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor. |
Merck Research Laboratories |
8201597 |
10 |
Non-peptide angiotensin II receptor antagonists: synthesis and biological activity of a series of novel 4,5-dihydro-4-oxo-3H-imidazo[4,5-c]pyridine derivatives. |
E. Merck |
8064808 |
202 |
Triazolinone biphenylsulfonamide derivatives as orally active angiotensin II antagonists with potent AT1 receptor affinity and enhanced AT2 affinity. |
Merck Research Laboratories |
8057285 |
44 |
Synthesis and SAR studies of novel triazolopyrimidine derivatives as potent, orally active angiotensin II receptor antagonists. |
Carpibem |
7990105 |
16 |
A highly potent, orally active imidazo[4,5-b]pyridine biphenylacylsulfonamide (MK-996; L-159,282): a new AT1-selective angiotensin II receptor antagonist. |
Merck Research Laboratories |
7799397 |
86 |
Triazolinone biphenylsulfonamides as angiotensin II receptor antagonists with high affinity for both the AT1 and AT2 subtypes. |
Merck Research Laboratories |
7636854 |
22 |
Balanced AT1/AT2 receptor antagonists. 4. XR510 and related 5-(3-amidopropanoyl)imidazoles possessing equal affinity for the AT1 and AT2 receptors. |
Dupont Pharmaceuticals |
7562905 |
258 |
Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes. |
Merck Research Laboratories |
7473594 |
11 |
4-(Heteroarylthio)-2-biphenylyltetrazoles as nonpeptide angiotensin II antagonists. |
Burroughs Wellcome |
7966154 |
15 |
Nonpeptide angiotensin II receptor antagonists. Synthesis, in vitro activity, and molecular modeling studies of N-[(heterobiaryl)methyl] imidazoles. |
Istituto Lusofarmaco |
7932534 |
29 |
Bromobenzofuran-based non-peptide antagonists of angiotensin II: GR138950, a potent antihypertensive agent with high oral bioavailability. |
Glaxo Research and Development |
2016730 |
14 |
1-(carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists. |
Smithkline Beecham Pharmaceuticals |
1433195 |
55 |
Imidazole-5-acrylic acids: potent nonpeptide angiotensin II receptor antagonists designed using a novel peptide pharmacophore model. |
Smithkline Beecham Pharmaceuticals |
26833890 |
18 |
Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease. |
Yogi Vemana University |
25665518 |
18 |
2,3-Dihydroquinazolin-4(1H)-one derivatives as potential non-peptidyl inhibitors of cathepsins B and H. |
Kurukshetra University |