The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
15509155 |
5 |
NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs. |
Universit£ |
9379447 |
20 |
Angiotensin analogues palmitoylated in positions 1 and 4. |
Universit£ |
| 19 |
Substituted lactam biphenyltetrazoles as angiotensin II mediated antihypertensives |
TBA |
| 40 |
Synthesis and In Vitro evaluation of fused ring heterocyle-containing angiotensin II antagonists. |
TBA |
22727371 |
22 |
Design, synthesis and biological activity of 6-substituted carbamoyl benzimidazoles as new nonpeptidic angiotensin II AT1 receptor antagonists. |
School of Chemical Engineering & The Environment |
18318468 |
39 |
Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems. |
Universit£ |
10821712 |
18 |
Quantized surface complementarity diversity (QSCD): a model based on small molecule-target complementarity. |
Neogenesis |
8576904 |
78 |
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy. |
Dupont Pharmaceuticals |
8340909 |
14 |
Excursions in drug discovery. |
Merck Research Laboratories |
| 32 |
L-161,638: A potent AT2selective quinazolinone angiotensin II binding inhibitor |
TBA |
| 17 |
(6-oxo-3-pyridazinyl)-benzimidazoles as potent angiotensin II receptor antagonists |
TBA |
22264484 |
28 |
Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists. |
Kyung Hee University |
22309912 |
28 |
Design, synthesis and biological evaluation of 6-substituted aminocarbonyl benzimidazole derivatives as nonpeptidic angiotensin II AT1 receptor antagonists. |
Beijing Institute of Technology |
21071232 |
78 |
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. |
The M. S. University of Baroda |
| 24 |
The design, binding affinity prediction and synthesis of macrocyclic angiotensin II AT1 and AT2 receptor antagonists |
TBA |
| 10 |
L-162,389: a potent orally active angiotensin II receptor antagonist with balanced affinity to both AT1 and AT2 receptor subtypes |
TBA |
| 17 |
AT1 selective angiotensin II antagonists with phenoxyphenylacetic acid as a biphenyl replacement part I |
TBA |
| 60 |
The SAR of 6-(N-alkyl-N-acyl)-2-propyl-3-[(2′-tetrazol-5-yl)biphen-4-yl)methyl]-quinazolinones as balanced affinity antagonists of the human AT1 and AT2 receptors |
TBA |
| 54 |
α-Phenoxyphenylacetic acid derived angiotensin II antagonists with low nanomolar AT1/AT2 receptor subtype affinity (Part II) |
TBA |
| 8 |
Substituted 1,3-benzodioxole & 1,3-benzodithiole -2- carboxylates and their tetrazole analogs with potent binding affinity to the angiotensin II AT1 receptor |
TBA |
| 56 |
Potent triazolinone-based angiotensin II receptor antagonists with equivalent affinity for both the AT1 and AT2 subtypes |
TBA |
| 134 |
Development of angiotensin II antagonists with equipotent affinity for human AT1 and AT2 receptor subtypes. |
TBA |
| 54 |
A new class of balanced AT1/AT2 angiotensin II antagonists: quinazolinone AII antagonists with acylsulfonamide and sulfonylcarbamate acidic functionalities |
TBA |
| 36 |
Quinazolinone Biphenyl Acylsulfonamides: A potent new class of angiotensin-II receptor antagonists |
TBA |
| 50 |
Potent imidazole angiotensinII antagonists: acyl sulfonamides and acyl sulfamides as tetrazole replacements |
TBA |
| 10 |
Evaluation of heterocyclic acid equivalents as tetrazole replacements in imidazopyridine-based nonpeptide angiotensin II receptor antagonists |
TBA |
| 8 |
Synthesis of new imidazo[1,2-b]pyridazine isosteres of potent imidazo[4,5-b]pyridine angiotensin II antagonists |
TBA |
| 22 |
Acidic phenols: a new class of potent nonpeptide angiotensin II receptor antagonists |
TBA |
| 24 |
Subtituted phenylthiophene benzoylsulfonamides with potent binding affinity to angiotensin II AT1 and AT2 receptors |
TBA |
| 42 |
Imidazo[4,5-b]pyridine-based AT1 / AT2 angiotensin II receptor antagonists |
TBA |
| 19 |
Triazolinones as nonpeptide angiotensin II antagonists. 2. discovery of a potent and orally active triazolinone acylsulfonamide |
TBA |
| 10 |
Angiotensin II receptor antagonists containing a phenylpyridine element. |
TBA |
| 45 |
Quinazolinones 2: QSAR and in vivo characterization of AT1 selective AII antagonists |
TBA |
| 23 |
Quinazolinones 1: design and synthesis of potent quinazolinone- containing AT1-selective angiotensin-II receptor antagonists |
TBA |
| 56 |
Synthesis and structure-activity relationships of a novel series of non-peptide AT2-selective angiotensin II receptor antagonists |
TBA |
17412584 |
26 |
Synthesis and biological activity of 2-alkylbenzimidazoles bearing a N-phenylpyrrole moiety as novel angiotensin II AT1 receptor antagonists. |
China Pharmaceutical University |
17064065 |
6 |
Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds. |
Università |
8496939 |
100 |
Nonpeptide angiotensin II antagonists derived from 4H-1,2,4-triazoles and 3H-imidazo[1,2-b][1,2,4]triazoles. |
Merck Research Laboratories |
8355255 |
103 |
Triazolinones as nonpeptide angiotensin II antagonists. 1. Synthesis and evaluation of potent 2,4,5-trisubstituted triazolinones. |
Merck Research Laboratories |
8277506 |
58 |
Non-peptide angiotensin II receptor antagonists. 2. Design, synthesis, and biological activity of N-substituted (phenylamino)phenylacetic acids and acyl sulfonamides. |
Merck Research Laboratories |
8277505 |
58 |
Non-peptide angiotensin II receptor antagonists. 1. Design, synthesis, and biological activity of N-substituted indoles and dihydroindoles. |
Merck Research Laboratories |
8246245 |
26 |
(Dipropylphenoxy)phenylacetic acids: a new generation of nonpeptide angiotensin II receptor antagonists. |
Merck Research Laboratories |
8246227 |
57 |
Nonpeptide angiotensin II antagonists derived from 1H-pyrazole-5-carboxylates and 4-aryl-1H-imidazole-5-carboxylates. |
Merck Research Laboratories |
8230109 |
18 |
A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor. |
Merck Research Laboratories |
8064808 |
202 |
Triazolinone biphenylsulfonamide derivatives as orally active angiotensin II antagonists with potent AT1 receptor affinity and enhanced AT2 affinity. |
Merck Research Laboratories |
7990105 |
16 |
A highly potent, orally active imidazo[4,5-b]pyridine biphenylacylsulfonamide (MK-996; L-159,282): a new AT1-selective angiotensin II receptor antagonist. |
Merck Research Laboratories |
7799397 |
86 |
Triazolinone biphenylsulfonamides as angiotensin II receptor antagonists with high affinity for both the AT1 and AT2 subtypes. |
Merck Research Laboratories |
7562905 |
258 |
Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes. |
Merck Research Laboratories |