BDBM205483 US9260417, 6
SMILES: CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
InChI Key: InChIKey=CMYHZFCJPORPHY-UHFFFAOYSA-N
Data: 14 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CDKL2 (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PITSLRE serine/threonine-protein kinase CDC2L1 (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase B-raf (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony stimulating factor receptor (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 2 (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAK 1/CDC42 (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM205483 (US9260417, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
AMITECH THERAPEUTIC SOLUTIONS, INC. US Patent | Assay Description For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc... | US Patent US9260417 (2016) BindingDB Entry DOI: 10.7270/Q270807Z | |||||||||||
More data for this Ligand-Target Pair |