BindingDB PrimarySearch

null

SMILES: Clc1ccc(cc1)-c1ccncc1NC(=O)c1ccnc(NC(=O)C2CC2)c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 52 hits for monomerid = 50613394
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Srms (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 33 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Interleukin-1 receptor-associated kinase 1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Golgi-associated PDZ and coiled-coil motif-containing protein (Homo sapiens)	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Mus musculus (mouse))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP/microtubule affinity-regulating kinase 4 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP/microtubule affinity-regulating kinase 3 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MARK2 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MARK1 (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50613394 (CHEMBL5278465) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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