Found 122 hits with Last Name = 'furey' and Initial = 'b' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50300196
(10-(4-hydroxyphenyl)-8,13,15-triazatetracyclo[9.6....)Show SMILES Oc1ccc(cc1)C1c2c[nH]c3nccc(-c4ccccc4NC1=O)c23 Show InChI InChI=1S/C21H15N3O2/c25-13-7-5-12(6-8-13)18-16-11-23-20-19(16)15(9-10-22-20)14-3-1-2-4-17(14)24-21(18)26/h1-11,18,25H,(H,22,23)(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| 0.00100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of recombinant JAK2 |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM50300196
(10-(4-hydroxyphenyl)-8,13,15-triazatetracyclo[9.6....)Show SMILES Oc1ccc(cc1)C1c2c[nH]c3nccc(-c4ccccc4NC1=O)c23 Show InChI InChI=1S/C21H15N3O2/c25-13-7-5-12(6-8-13)18-16-11-23-20-19(16)15(9-10-22-20)14-3-1-2-4-17(14)24-21(18)26/h1-11,18,25H,(H,22,23)(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
| Article PubMed
| 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of recombinant JAK3 |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM50300196
(10-(4-hydroxyphenyl)-8,13,15-triazatetracyclo[9.6....)Show SMILES Oc1ccc(cc1)C1c2c[nH]c3nccc(-c4ccccc4NC1=O)c23 Show InChI InChI=1S/C21H15N3O2/c25-13-7-5-12(6-8-13)18-16-11-23-20-19(16)15(9-10-22-20)14-3-1-2-4-17(14)24-21(18)26/h1-11,18,25H,(H,22,23)(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
| Article PubMed
| 0.00500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of recombinant JAK3 |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50300196
(10-(4-hydroxyphenyl)-8,13,15-triazatetracyclo[9.6....)Show SMILES Oc1ccc(cc1)C1c2c[nH]c3nccc(-c4ccccc4NC1=O)c23 Show InChI InChI=1S/C21H15N3O2/c25-13-7-5-12(6-8-13)18-16-11-23-20-19(16)15(9-10-22-20)14-3-1-2-4-17(14)24-21(18)26/h1-11,18,25H,(H,22,23)(H,24,26) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of ALK |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50300196
(10-(4-hydroxyphenyl)-8,13,15-triazatetracyclo[9.6....)Show SMILES Oc1ccc(cc1)C1c2c[nH]c3nccc(-c4ccccc4NC1=O)c23 Show InChI InChI=1S/C21H15N3O2/c25-13-7-5-12(6-8-13)18-16-11-23-20-19(16)15(9-10-22-20)14-3-1-2-4-17(14)24-21(18)26/h1-11,18,25H,(H,22,23)(H,24,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
| Article PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of cKit |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50300198
(5-chloro-3-phenyl-1H-pyrrolo[2,3-b]pyridine | CHEM...)Show InChI InChI=1S/C13H9ClN2/c14-10-6-11-12(8-16-13(11)15-7-10)9-4-2-1-3-5-9/h1-8H,(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of recombinant JAK2 |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 2
(Homo sapiens (Human)) | BDBM50300196
(10-(4-hydroxyphenyl)-8,13,15-triazatetracyclo[9.6....)Show SMILES Oc1ccc(cc1)C1c2c[nH]c3nccc(-c4ccccc4NC1=O)c23 Show InChI InChI=1S/C21H15N3O2/c25-13-7-5-12(6-8-13)18-16-11-23-20-19(16)15(9-10-22-20)14-3-1-2-4-17(14)24-21(18)26/h1-11,18,25H,(H,22,23)(H,24,26) | MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
| Article PubMed
| 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of GCK |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50300197
(4-phenyl-7H-pyrrolo[2,3-d]pyrimidine | CHEMBL57897...)Show InChI InChI=1S/C12H9N3/c1-2-4-9(5-3-1)11-10-6-7-13-12(10)15-8-14-11/h1-8H,(H,13,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of recombinant JAK2 |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596154
(CHEMBL5169448) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596176
(CHEMBL5185729)Show SMILES Fc1cncc(c1)-n1ccc(NC(=O)C2(CC2)c2c(F)cccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596163
(CHEMBL5206398) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596161
(CHEMBL5203823)Show SMILES Fc1cncc(c1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596146
(CHEMBL5204141) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596164
(CHEMBL5172768) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596162
(CHEMBL5185644)Show SMILES Fc1ccc(cn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596160
(CHEMBL5205200) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596145
(CHEMBL5199478)Show SMILES C[C@H](C(=O)Nc1ccn(n1)-c1ccccc1)c1ccccc1 |r| | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596133
(CHEMBL5081193)Show SMILES Fc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596157
(CHEMBL5194186)Show SMILES COc1cc(ccn1)-n1ccc(NC(=O)C2(CC2)c2ccccc2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596135
(CHEMBL5190392) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596143
(CHEMBL5200554) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596155
(CHEMBL5174762) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596172
(CHEMBL5204609)Show SMILES Fc1ccc(cc1)C1(CC1)C(=O)Nc1ccn(n1)-c1cncc(F)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596175
(CHEMBL5192322)Show SMILES Fc1cncc(c1)-n1ccc(NC(=O)C2(CC2)c2ccc(cc2)C#N)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596165
(CHEMBL5202816)Show SMILES Fc1cncc(c1)-n1ccc(NC(=O)C2(CC2)c2ccccc2Cl)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596177
(CHEMBL5188173)Show SMILES Fc1cncc(c1)-n1ccc(NC(=O)C2(CC2)c2cccc(F)c2F)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596150
(CHEMBL5182190)Show SMILES FC1(F)CC1(C(=O)Nc1ccn(n1)-c1ccccc1)c1ccccc1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596178
(CHEMBL5202203)Show SMILES Fc1ccc(F)c(c1)C1(CC1)C(=O)Nc1ccn(n1)-c1cncc(F)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596170
(CHEMBL5200718)Show SMILES COc1cccc(c1)C1(CC1)C(=O)Nc1ccn(n1)-c1cncc(F)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596169
(CHEMBL5190417)Show SMILES Fc1cccc(c1)C1(CC1)C(=O)Nc1ccn(n1)-c1cncc(F)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596144
(CHEMBL5194918)Show SMILES C[C@@H](C(=O)Nc1ccn(n1)-c1ccccc1)c1ccccc1 |r| | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596153
(CHEMBL5202062) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM50300196
(10-(4-hydroxyphenyl)-8,13,15-triazatetracyclo[9.6....)Show SMILES Oc1ccc(cc1)C1c2c[nH]c3nccc(-c4ccccc4NC1=O)c23 Show InChI InChI=1S/C21H15N3O2/c25-13-7-5-12(6-8-13)18-16-11-23-20-19(16)15(9-10-22-20)14-3-1-2-4-17(14)24-21(18)26/h1-11,18,25H,(H,22,23)(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Inhibition of JAK2 in human TF1 cells assessed as inhibition of GMCSF-induced STAT5 phosphorylation by flow cytometry |
J Med Chem 52: 7938-41 (2009)
Checked by Author Article DOI: 10.1021/jm901383u BindingDB Entry DOI: 10.7270/Q2GF0TK0 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596134
(CHEMBL5178289) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596148
(CHEMBL5174196) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596171
(CHEMBL5202263)Show SMILES Fc1cncc(c1)-n1ccc(NC(=O)C2(CC2)c2cccc(c2)C#N)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596173
(CHEMBL5207495)Show SMILES Fc1cncc(c1)-n1ccc(NC(=O)C2(CC2)c2ccc(Cl)cc2)n1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596166
(CHEMBL5190980)Show SMILES Cc1ccccc1C1(CC1)C(=O)Nc1ccn(n1)-c1cncc(F)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596163
(CHEMBL5206398) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596154
(CHEMBL5169448) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50596146
(CHEMBL5204141) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |
Elongation of very long chain fatty acids protein 1
(Homo sapiens (Human)) | BDBM50139066
(CHEMBL2403494)Show InChI InChI=1S/C17H14N2OS/c20-16(11-13-7-3-1-4-8-13)19-17-18-15(12-21-17)14-9-5-2-6-10-14/h1-10,12H,11H2,(H,18,19,20) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00944 BindingDB Entry DOI: 10.7270/Q22R3WPP |
More data for this Ligand-Target Pair | |