Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095611 (CHEMBL356750 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095611 (CHEMBL356750 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533609 (CHEMBL4544583) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.142 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533620 (CHEMBL4476699) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.153 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533625 (CHEMBL4552939) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50369770 (CHEMBL1788140) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533617 (CHEMBL4555307) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.331 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533621 (CHEMBL4521947) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.341 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50530577 (CHEMBL4451683 | US11337971, Compound (+-)-19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.362 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533612 (CHEMBL4471669) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.363 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533624 (CHEMBL4461461) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.621 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533615 (CHEMBL4577414) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.941 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533619 (CHEMBL4517102) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.985 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533623 (CHEMBL4543524) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533610 (CHEMBL4564507) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095629 (CHEMBL147983 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095619 (CHEMBL147950 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50533620 (CHEMBL4476699) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]DOI from 5-HT2A receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50533612 (CHEMBL4471669) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533618 (CHEMBL4459533) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50533622 (CHEMBL4469777) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]DOI from 5-HT2A receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50533619 (CHEMBL4517102) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]DOI from 5-HT2A receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095631 (CHEMBL146332 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50533622 (CHEMBL4469777) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]DOI from 5-HT2C receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533626 (CHEMBL4517898) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50533615 (CHEMBL4577414) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095630 (CHEMBL356552 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095618 (CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095618 (CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50533609 (CHEMBL4544583) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]DOI from 5-HT2A receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50533608 (CHEMBL4441358) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]DOI from 5-HT2C receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095619 (CHEMBL147950 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50533609 (CHEMBL4544583) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50533617 (CHEMBL4555307) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095611 (CHEMBL356750 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095611 (CHEMBL356750 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50533620 (CHEMBL4476699) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50530576 (CHEMBL4476394 | US11337971, Compound (+-)-29) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50533625 (CHEMBL4552939) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50533608 (CHEMBL4441358) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]DOI from 5-HT2A receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50095629 (CHEMBL147983 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI. | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50095611 (CHEMBL356750 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI. | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50095611 (CHEMBL356750 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI. | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50533611 (CHEMBL4516799) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation c... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50533624 (CHEMBL4461461) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50533623 (CHEMBL4543524) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ... | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50005118 ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to dopamine D3 receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50005118 ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to dopamine D2 receptor (unknown origin) | J Med Chem 59: 7634-50 (2016) Article DOI: 10.1021/acs.jmedchem.6b00860 BindingDB Entry DOI: 10.7270/Q2NS0ZDD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50095629 (CHEMBL147983 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporter | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50369771 (CHEMBL1744173) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharm-Eco Laboratories Curated by ChEMBL | Assay Description Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTI | J Med Chem 43: 4981-92 (2001) BindingDB Entry DOI: 10.7270/Q2SX6DXD | |||||||||||
More data for this Ligand-Target Pair |
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