Compile Data Set for Download or QSAR

Found 248 hits with Last Name = 'besong' and Initial = 'ge'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139913 (US8895745, 375) Show SMILES Cn1cnc(c1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C20H17F3N6O/c1-28-10-16(26-12-28)13-5-6-29-17(9-24-18(29)8-13)14-3-2-4-15(7-14)27-19(30)25-11-20(21,22)23/h2-10,12H,11H2,1H3,(H2,25,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.490	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139918 (US8895745, 401) Show SMILES OCCn1cc(cn1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C21H19F3N6O2/c22-21(23,24)13-26-20(32)28-17-3-1-2-15(8-17)18-11-25-19-9-14(4-5-30(18)19)16-10-27-29(12-16)6-7-31/h1-5,8-12,31H,6-7,13H2,(H2,26,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.704	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139909 (US8895745, 310) Show SMILES Cc1nnc(s1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C19H15F3N6OS/c1-11-26-27-17(30-11)13-5-6-28-15(9-23-16(28)8-13)12-3-2-4-14(7-12)25-18(29)24-10-19(20,21)22/h2-9H,10H2,1H3,(H2,24,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.780	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139914 (US8895745, 378) Show SMILES Cc1c(nnn1C)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C20H18F3N7O/c1-12-18(27-28-29(12)2)14-6-7-30-16(10-24-17(30)9-14)13-4-3-5-15(8-13)26-19(31)25-11-20(21,22)23/h3-10H,11H2,1-2H3,(H2,25,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.790	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139920 (US8895745, 412) Show SMILES Cc1nc(c(C)n1C)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C22H21F3N6O/c1-13-20(28-14(2)30(13)3)16-7-8-31-18(11-26-19(31)10-16)15-5-4-6-17(9-15)29-21(32)27-12-22(23,24)25/h4-11H,12H2,1-3H3,(H2,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.24	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139924 (US8895745, 402) Show SMILES NCCn1cc(cn1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C21H20F3N7O/c22-21(23,24)13-27-20(32)29-17-3-1-2-15(8-17)18-11-26-19-9-14(4-6-31(18)19)16-10-28-30(12-16)7-5-25/h1-4,6,8-12H,5,7,13,25H2,(H2,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139915 (US8895745, 384) Show SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(ccn12)-c1nncs1 Show InChI InChI=1S/C18H13F3N6OS/c19-18(20,21)9-23-17(28)25-13-3-1-2-11(6-13)14-8-22-15-7-12(4-5-27(14)15)16-26-24-10-29-16/h1-8,10H,9H2,(H2,23,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139921 (US8895745, 416) Show SMILES Cc1cn(cn1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C20H17F3N6O/c1-13-10-28(12-26-13)16-5-6-29-17(9-24-18(29)8-16)14-3-2-4-15(7-14)27-19(30)25-11-20(21,22)23/h2-10,12H,11H2,1H3,(H2,25,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.18	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139922 (US8895745, 421) Show SMILES Cc1ccc(nn1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C21H17F3N6O/c1-13-5-6-17(29-28-13)14-7-8-30-18(11-25-19(30)10-14)15-3-2-4-16(9-15)27-20(31)26-12-21(22,23)24/h2-11H,12H2,1H3,(H2,26,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139923 (US8895745, 422) Show SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(ccn12)-c1ncns1 Show InChI InChI=1S/C18H13F3N6OS/c19-18(20,21)9-23-17(28)26-13-3-1-2-11(6-13)14-8-22-15-7-12(4-5-27(14)15)16-24-10-25-29-16/h1-8,10H,9H2,(H2,23,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139908 (US8895745, 59) Show SMILES Fc1ccc(cc1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C22H16F4N4O/c23-17-6-4-14(5-7-17)15-8-9-30-19(12-27-20(30)11-15)16-2-1-3-18(10-16)29-21(31)28-13-22(24,25)26/h1-12H,13H2,(H2,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139917 (US8895745, 399) Show SMILES Cc1nsc(n1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C19H15F3N6OS/c1-11-25-17(30-27-11)13-5-6-28-15(9-23-16(28)8-13)12-3-2-4-14(7-12)26-18(29)24-10-19(20,21)22/h2-9H,10H2,1H3,(H2,24,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.74	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139910 (US8895745, 329) Show SMILES Cc1nnc(o1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C19H15F3N6O2/c1-11-26-27-17(30-11)13-5-6-28-15(9-23-16(28)8-13)12-3-2-4-14(7-12)25-18(29)24-10-19(20,21)22/h2-9H,10H2,1H3,(H2,24,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139912 (US8895745, 359) Show SMILES CN(N)\N=C(/N)c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C18H19F3N8O/c1-28(23)27-16(22)12-5-6-29-14(9-24-15(29)8-12)11-3-2-4-13(7-11)26-17(30)25-10-18(19,20)21/h2-9H,10,23H2,1H3,(H2,22,27)(H2,25,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.4	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139916 (US8895745, 396) Show SMILES CC#Cc1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C19H15F3N4O/c1-2-4-13-7-8-26-16(11-23-17(26)9-13)14-5-3-6-15(10-14)25-18(27)24-12-19(20,21)22/h3,5-11H,12H2,1H3,(H2,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18.3	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139911 (US8895745, 354) Show SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(ccn12)C(=N)OC(S)=N Show InChI InChI=1S/C18H15F3N6O2S/c19-18(20,21)9-25-17(28)26-12-3-1-2-10(6-12)13-8-24-14-7-11(4-5-27(13)14)15(22)29-16(23)30/h1-8,22H,9H2,(H2,23,30)(H2,25,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.2	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM139919 (US8895745, 407) Show SMILES Cc1nnc(o1)-c1ccn2c(cnc2c1)-c1cncc(NC(=O)NCC(F)(F)F)c1 Show InChI InChI=1S/C18H14F3N7O2/c1-10-26-27-16(30-10)11-2-3-28-14(8-23-15(28)5-11)12-4-13(7-22-6-12)25-17(29)24-9-18(19,20)21/h2-8H,9H2,1H3,(H2,24,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	7.5	n/a
Astex Therapeutics Limited US Patent					Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ...				US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183589 (US9145354, 241) Show SMILES CC[C@@H](N[C@H](C)CC(=O)NCCN)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F |r| Show InChI InChI=1S/C21H27ClFN5O2/c1-3-16(28-12(2)10-18(29)26-9-8-24)14-5-6-15(22)19(20(14)23)21(30)13-4-7-17(25)27-11-13/h4-7,11-12,16,28H,3,8-10,24H2,1-2H3,(H2,25,27)(H,26,29)/t12-,16-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183547 (US9145354, 182) Show SMILES CC[C@H](NCCCO)c1ccc(Cl)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C19H21ClFNO2/c1-2-16(22-11-6-12-23)14-9-10-15(20)17(18(14)21)19(24)13-7-4-3-5-8-13/h3-5,7-10,16,22-23H,2,6,11-12H2,1H3/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183530 (US9145354, 157) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(F)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C20H22F2N2O2/c1-3-16(24-12(2)11-17(23)25)14-9-10-15(21)18(19(14)22)20(26)13-7-5-4-6-8-13/h4-10,12,16,24H,3,11H2,1-2H3,(H2,23,25)/t12-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183490 (US9145354, 97) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc(F)cc2)c1F |r| Show InChI InChI=1S/C20H21ClF2N2O2/c1-3-16(25-11(2)10-17(24)26)14-8-9-15(21)18(19(14)23)20(27)12-4-6-13(22)7-5-12/h4-9,11,16,25H,3,10H2,1-2H3,(H2,24,26)/t11-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183527 (US9145354, 152) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(OC)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C21H25FN2O3/c1-4-16(24-13(2)12-18(23)25)15-10-11-17(27-3)19(20(15)22)21(26)14-8-6-5-7-9-14/h5-11,13,16,24H,4,12H2,1-3H3,(H2,23,25)/t13-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183469 (US9145354, 69) Show SMILES COc1cc(ccc1C#N)C(=O)c1c(Cl)ccc([C@H](N)C2CC2)c1F |r| Show InChI InChI=1S/C19H16ClFN2O2/c1-25-15-8-11(4-5-12(15)9-22)19(24)16-14(20)7-6-13(17(16)21)18(23)10-2-3-10/h4-8,10,18H,2-3,23H2,1H3/t18-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183540 (US9145354, 171) Show SMILES CC[C@H](NCCO)c1ccc(Cl)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C18H19ClFNO2/c1-2-15(21-10-11-22)13-8-9-14(19)16(17(13)20)18(23)12-6-4-3-5-7-12/h3-9,15,21-22H,2,10-11H2,1H3/t15-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183480 (US9145354, 84) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C20H22ClFN2O2/c1-3-16(24-12(2)11-17(23)25)14-9-10-15(21)18(19(14)22)20(26)13-7-5-4-6-8-13/h4-10,12,16,24H,3,11H2,1-2H3,(H2,23,25)/t12-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183434 (US9145354, 32) Show SMILES N[C@H](C1CC1)c1ccc(Cl)c(C(=O)c2ccc(cc2)C#N)c1F |r| Show InChI InChI=1S/C18H14ClFN2O/c19-14-8-7-13(17(22)11-5-6-11)16(20)15(14)18(23)12-3-1-10(9-21)2-4-12/h1-4,7-8,11,17H,5-6,22H2/t17-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183481 (US9145354, 85) Show SMILES CC[C@H](N[C@H](C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C20H22ClFN2O2/c1-3-16(24-12(2)11-17(23)25)14-9-10-15(21)18(19(14)22)20(26)13-7-5-4-6-8-13/h4-10,12,16,24H,3,11H2,1-2H3,(H2,23,25)/t12-,16+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183545 (US9145354, 179) Show SMILES CCC(NC(C)(C)CO)c1ccc(Cl)c(C(=O)c2ccccc2)c1F Show InChI InChI=1S/C20H23ClFNO2/c1-4-16(23-20(2,3)12-24)14-10-11-15(21)17(18(14)22)19(25)13-8-6-5-7-9-13/h5-11,16,23-24H,4,12H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183631 (US9145354, 298) Show SMILES CC[C@H](NC(=O)C[C@@H](N)C(C)C)c1ccc(Cl)c(C(=O)c2cccnc2)c1F |r| Show InChI InChI=1S/C21H25ClFN3O2/c1-4-17(26-18(27)10-16(24)12(2)3)14-7-8-15(22)19(20(14)23)21(28)13-6-5-9-25-11-13/h5-9,11-12,16-17H,4,10,24H2,1-3H3,(H,26,27)/t16-,17+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183636 (US9145354, 303) Show SMILES CC[C@H](NC(=O)CCN)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F |r| Show InChI InChI=1S/C18H20ClFN4O2/c1-2-13(24-15(25)7-8-21)11-4-5-12(19)16(17(11)20)18(26)10-3-6-14(22)23-9-10/h3-6,9,13H,2,7-8,21H2,1H3,(H2,22,23)(H,24,25)/t13-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM60671 (BDBM183487 | US9145354, 92) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc(cc2)C#N)c1F |r| Show InChI InChI=1S/C21H21ClFN3O2/c1-3-17(26-12(2)10-18(25)27)15-8-9-16(22)19(20(15)23)21(28)14-6-4-13(11-24)5-7-14/h4-9,12,17,26H,3,10H2,1-2H3,(H2,25,27)/t12-,17+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183526 (US9145354, 150) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(C)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C21H25FN2O2/c1-4-17(24-14(3)12-18(23)25)16-11-10-13(2)19(20(16)22)21(26)15-8-6-5-7-9-15/h5-11,14,17,24H,4,12H2,1-3H3,(H2,23,25)/t14-,17+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183497 (US9145354, 108) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccns2)c1F |r| Show InChI InChI=1S/C17H19ClFN3O2S/c1-3-12(22-9(2)8-14(20)23)10-4-5-11(18)15(16(10)19)17(24)13-6-7-21-25-13/h4-7,9,12,22H,3,8H2,1-2H3,(H2,20,23)/t9-,12+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM60669 (US9145354, 24) Show SMILES CC[C@H](N)c1ccc(Cl)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C16H15ClFNO/c1-2-13(19)11-8-9-12(17)14(15(11)18)16(20)10-6-4-3-5-7-10/h3-9,13H,2,19H2,1H3/t13-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183413 (US9145354, 9) Show SMILES CC[C@@H](N)c1ccc(Cl)c(C(=O)c2ccc(C=N)cc2)c1F |r| Show InChI InChI=1S/C17H16ClFN2O/c1-2-14(21)12-7-8-13(18)15(16(12)19)17(22)11-5-3-10(9-20)4-6-11/h3-9,14,20H,2,21H2,1H3/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183493 (US9145354, 103) Show SMILES C[C@@H](CC(N)=O)N[C@H](C1CC1)c1ccc(Cl)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C21H22ClFN2O2/c1-12(11-17(24)26)25-20(13-7-8-13)15-9-10-16(22)18(19(15)23)21(27)14-5-3-2-4-6-14/h2-6,9-10,12-13,20,25H,7-8,11H2,1H3,(H2,24,26)/t12-,20+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183562 (US9145354, 200) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(OC)c(C(=O)c2ccc(F)cc2)c1F |r| Show InChI InChI=1S/C21H24F2N2O3/c1-4-16(25-12(2)11-18(24)26)15-9-10-17(28-3)19(20(15)23)21(27)13-5-7-14(22)8-6-13/h5-10,12,16,25H,4,11H2,1-3H3,(H2,24,26)/t12-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183577 (US9145354, 224) Show SMILES COc1ccc([C@H](N[C@@H](C)CC(N)=O)C2CC2)c(F)c1C(=O)c1cccc(F)c1 |r| Show InChI InChI=1S/C22H24F2N2O3/c1-12(10-18(25)27)26-21(13-6-7-13)16-8-9-17(29-2)19(20(16)24)22(28)14-4-3-5-15(23)11-14/h3-5,8-9,11-13,21,26H,6-7,10H2,1-2H3,(H2,25,27)/t12-,21+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM60704 (BDBM183583 | US9145354, 220 | US9145354, 267) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc(N)c(Cl)c2)c1F |r| Show InChI InChI=1S/C20H22Cl2FN3O2/c1-3-16(26-10(2)8-17(25)27)12-5-6-13(21)18(19(12)23)20(28)11-4-7-15(24)14(22)9-11/h4-7,9-10,16,26H,3,8,24H2,1-2H3,(H2,25,27)/t10-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183489 (US9145354, 95) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(Cl)c(C(=O)c2cccc(F)c2)c1F |r| Show InChI InChI=1S/C20H21ClF2N2O2/c1-3-16(25-11(2)9-17(24)26)14-7-8-15(21)18(19(14)23)20(27)12-5-4-6-13(22)10-12/h4-8,10-11,16,25H,3,9H2,1-2H3,(H2,24,26)/t11-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183514 (US9145354, 134) Show SMILES C[C@@H](CC(N)=O)N[C@H](C1CC1)c1ccc(Cl)c(C(=O)c2ccncc2)c1F |r| Show InChI InChI=1S/C20H21ClFN3O2/c1-11(10-16(23)26)25-19(12-2-3-12)14-4-5-15(21)17(18(14)22)20(27)13-6-8-24-9-7-13/h4-9,11-12,19,25H,2-3,10H2,1H3,(H2,23,26)/t11-,19+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183544 (US9145354, 178) Show SMILES CC[C@H](N[C@H](C)CO)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F |r| Show InChI InChI=1S/C18H21ClFN3O2/c1-3-14(23-10(2)9-24)12-5-6-13(19)16(17(12)20)18(25)11-4-7-15(21)22-8-11/h4-8,10,14,23-24H,3,9H2,1-2H3,(H2,21,22)/t10-,14+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM60668 (BDBM183408 | US9145354, 23) Show SMILES CC[C@@H](N)c1ccc(Cl)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C16H15ClFNO/c1-2-13(19)11-8-9-12(17)14(15(11)18)16(20)10-6-4-3-5-7-10/h3-9,13H,2,19H2,1H3/t13-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183405 (US9145354, 1) Show SMILES CC[C@@H](N)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F |r| Show InChI InChI=1S/C15H15ClFN3O/c1-2-11(18)9-4-5-10(16)13(14(9)17)15(21)8-3-6-12(19)20-7-8/h3-7,11H,2,18H2,1H3,(H2,19,20)/t11-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183501 (US9145354, 113) Show SMILES CC[C@@H](NC(C)(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2cccnc2)c1F |r| Show InChI InChI=1S/C20H23ClFN3O2/c1-4-15(25-20(2,3)10-16(23)26)13-7-8-14(21)17(18(13)22)19(27)12-6-5-9-24-11-12/h5-9,11,15,25H,4,10H2,1-3H3,(H2,23,26)/t15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183570 (US9145354, 212) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(OC)c(C(=O)c2cccc(F)c2)c1F |r| Show InChI InChI=1S/C21H24F2N2O3/c1-4-16(25-12(2)10-18(24)26)15-8-9-17(28-3)19(20(15)23)21(27)13-6-5-7-14(22)11-13/h5-9,11-12,16,25H,4,10H2,1-3H3,(H2,24,26)/t12-,16+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183596 (US9145354, 250) Show SMILES CC[C@@H](NC(C)(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F |r| Show InChI InChI=1S/C20H24ClFN4O2/c1-4-14(26-20(2,3)9-16(24)27)12-6-7-13(21)17(18(12)22)19(28)11-5-8-15(23)25-10-11/h5-8,10,14,26H,4,9H2,1-3H3,(H2,23,25)(H2,24,27)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183537 (US9145354, 167) Show SMILES CC[C@@H](NCCC(N)=O)c1ccc(Cl)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C19H20ClFN2O2/c1-2-15(23-11-10-16(22)24)13-8-9-14(20)17(18(13)21)19(25)12-6-4-3-5-7-12/h3-9,15,23H,2,10-11H2,1H3,(H2,22,24)/t15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183569 (US9145354, 210) Show SMILES COc1ccc([C@H](N[C@@H](C)CC(N)=O)C2CC2)c(F)c1C(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H24F2N2O3/c1-12(11-18(25)27)26-21(13-3-4-13)16-9-10-17(29-2)19(20(16)24)22(28)14-5-7-15(23)8-6-14/h5-10,12-13,21,26H,3-4,11H2,1-2H3,(H2,25,27)/t12-,21+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183586 (US9145354, 238) Show SMILES C[C@@H](CC(N)=O)N[C@H](C1CC1)c1ccc(Cl)c(C(=O)c2ccc(cn2)C#N)c1F |r| Show InChI InChI=1S/C21H20ClFN4O2/c1-11(8-17(25)28)27-20(13-3-4-13)14-5-6-15(22)18(19(14)23)21(29)16-7-2-12(9-24)10-26-16/h2,5-7,10-11,13,20,27H,3-4,8H2,1H3,(H2,25,28)/t11-,20+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
					More data for this Ligand-Target Pair

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