Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V2 receptor (Rattus norvegicus (Rat)) | BDBM35709![]() (YM-35278) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.400 | -53.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35683![]() (5H-1-benzazepin-5-ylidene acetamide, 1k) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.40 | -48.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35673![]() (5H-1-benzazepin-5-ylidene acetamide, 1a | BMC16952...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.80 | -47.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35673![]() (5H-1-benzazepin-5-ylidene acetamide, 1a | BMC16952...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.80 | -47.2 | n/a | n/a | 1.80 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35677![]() (5H-1-benzazepin-5-ylidene acetamide, 1e) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 5.60 | -46.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35700![]() (5H-1-benzazepin-5-ylidene acetamide, 10g) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 6 | -46.6 | n/a | n/a | >1.00E+4 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35681![]() (5H-1-benzazepin-5-ylidene acetamide, 1i) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 7.40 | -46.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35699![]() (5H-1-benzazepin-5-ylidene acetamide, 10f) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 9.10 | -45.6 | n/a | n/a | >1.00E+4 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35695![]() (5H-1-benzazepin-5-ylidene acetamide, 10b) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 9.20 | -45.6 | n/a | n/a | 61.9 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35666![]() (BMC173130 Compound 1t | benzazepinelidene acetamid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 9.70 | -45.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35666![]() (BMC173130 Compound 1t | benzazepinelidene acetamid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 9.70 | -45.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35679![]() (5H-1-benzazepin-5-ylidene acetamide, 1g) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 10 | -45.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35686![]() (5H-1-benzazepin-5-ylidene acetamide, 1n) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 11 | -45.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35684![]() (5H-1-benzazepin-5-ylidene acetamide, 1l) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 11 | -45.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35680![]() (5H-1-benzazepin-5-ylidene acetamide, 1h) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 11 | -45.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35685![]() (5H-1-benzazepin-5-ylidene acetamide, 1m) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 11 | -45.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35706![]() (5H-1-benzazepin-5-ylidene acetamide, 10m) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 11 | -45.1 | n/a | n/a | 646 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35698![]() (5H-1-benzazepin-5-ylidene acetamide, 10e) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 11 | -45.1 | n/a | n/a | >1.00E+4 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35694![]() (5H-1-benzazepin-5-ylidene acetamide, 1w) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 11 | -45.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35687![]() (5H-1-benzazepin-5-ylidene acetamide, 1o) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 12 | -44.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35669![]() (benzazepinelidene acetamide derivative, 1d) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 13 | -44.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35669![]() (benzazepinelidene acetamide derivative, 1d) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 13 | -44.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35691![]() (5H-1-benzazepin-5-ylidene acetamide, 1s) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 13 | -45.0 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35672![]() (benzazepinelidene acetamide derivative, 1g) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 14 | -44.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35682![]() (5H-1-benzazepin-5-ylidene acetamide, 1j) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 14 | -44.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35703![]() (5H-1-benzazepin-5-ylidene acetamide, 10j | racemat...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 14 | -44.5 | n/a | n/a | 1.25 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35671![]() (benzazepinelidene acetamide derivative, 1f) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 14 | -44.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35705![]() (5H-1-benzazepin-5-ylidene acetamide, 10l) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 14 | -44.5 | n/a | n/a | 104 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35675![]() (5H-1-benzazepin-5-ylidene acetamide, 1c) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 15 | -44.7 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35670![]() (benzazepinelidene acetamide derivative, 1e) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 16 | -44.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35704![]() (5H-1-benzazepin-5-ylidene acetamide, 10k) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 16 | -44.2 | n/a | n/a | 1.10E+3 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35678![]() (5H-1-benzazepin-5-ylidene acetamide, 1f) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 16 | -44.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35671![]() (benzazepinelidene acetamide derivative, 1f) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 17 | -44.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35697![]() (5H-1-benzazepin-5-ylidene acetamide, 10d) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 18 | -43.9 | n/a | n/a | >1.00E+4 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35691![]() (5H-1-benzazepin-5-ylidene acetamide, 1s) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 18 | -43.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Rattus norvegicus (Rat)) | BDBM35673![]() (5H-1-benzazepin-5-ylidene acetamide, 1a | BMC16952...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 19 | -43.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35676![]() (5H-1-benzazepin-5-ylidene acetamide, 1d) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 19 | -43.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35675![]() (5H-1-benzazepin-5-ylidene acetamide, 1c) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 20 | -43.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50358251![]() (CHEMBL1922344) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of human factor 10A using chromogenic substrate S2222 by dixon plot analysis | J Med Chem 54: 8051-65 (2011) Article DOI: 10.1021/jm200868m BindingDB Entry DOI: 10.7270/Q2D50ND9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35701![]() (5H-1-benzazepin-5-ylidene acetamide, 10h) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 20 | -43.6 | n/a | n/a | >1.00E+4 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35696![]() (5H-1-benzazepin-5-ylidene acetamide, 10c) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 21 | -43.5 | n/a | n/a | >1.00E+4 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35674![]() (5H-1-benzazepin-5-ylidene acetamide, 1b) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 21 | -43.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35702![]() (5H-1-benzazepin-5-ylidene acetamide, 10i) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 22 | -43.4 | n/a | n/a | 3.13 | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 16: 9524-35 (2008) Article DOI: 10.1016/j.bmc.2008.09.039 BindingDB Entry DOI: 10.7270/Q2125R12 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35693![]() (5H-1-benzazepin-5-ylidene acetamide, 1v) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 22 | -43.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35681![]() (5H-1-benzazepin-5-ylidene acetamide, 1i) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 22 | -43.7 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35689![]() (5H-1-benzazepin-5-ylidene acetamide, 1q) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 25 | -43.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35673![]() (5H-1-benzazepin-5-ylidene acetamide, 1a | BMC16952...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 26 | -43.3 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35688![]() (5H-1-benzazepin-5-ylidene acetamide, 1p) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 27 | -42.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35666![]() (BMC173130 Compound 1t | benzazepinelidene acetamid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 28 | -43.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 3130-41 (2009) Article DOI: 10.1016/j.bmc.2009.03.001 BindingDB Entry DOI: 10.7270/Q24T6GQM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35666![]() (BMC173130 Compound 1t | benzazepinelidene acetamid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 28 | -42.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
More data for this Ligand-Target Pair |
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