Compile Data Set for Download or QSAR

Found 44 hits with Last Name = 'leroy' and Initial = 'i'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149327 (US8962837, 12) Show SMILES Cn1cc(Cl)nc(N2CCC(CC2)Oc2cc(F)ccc2Cl)c1=O Show InChI InChI=1S/C16H16Cl2FN3O2/c1-21-9-14(18)20-15(16(21)23)22-6-4-11(5-7-22)24-13-8-10(19)2-3-12(13)17/h2-3,8-9,11H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149331 (US8962837, 18) Show SMILES Fc1ccc(Cl)c(OC2CCN(CC2)c2nccnn2)c1 Show InChI InChI=1S/C14H14ClFN4O/c15-12-2-1-10(16)9-13(12)21-11-3-7-20(8-4-11)14-17-5-6-18-19-14/h1-2,5-6,9,11H,3-4,7-8H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149340 (US8962837, 36) Show SMILES FC(F)(F)c1ccccc1NC1CCN(CC1)c1nccnn1 Show InChI InChI=1S/C15H16F3N5/c16-15(17,18)12-3-1-2-4-13(12)21-11-5-9-23(10-6-11)14-19-7-8-20-22-14/h1-4,7-8,11,21H,5-6,9-10H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149338 (US8962837, 33) Show SMILES Fc1cc(Br)c(OC2CCN(CC2)c2nccnn2)cc1F Show InChI InChI=1S/C14H13BrF2N4O/c15-10-7-11(16)12(17)8-13(10)22-9-1-5-21(6-2-9)14-18-3-4-19-20-14/h3-4,7-9H,1-2,5-6H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149337 (US8962837, 32) Show SMILES [O-][N+](=O)c1ccc(Cl)c(OC2CCN(CC2)c2nccnn2)c1 Show InChI InChI=1S/C14H14ClN5O3/c15-12-2-1-10(20(21)22)9-13(12)23-11-3-7-19(8-4-11)14-16-5-6-17-18-14/h1-2,5-6,9,11H,3-4,7-8H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149333 (US8962837, 25) Show SMILES Cc1cnnc(n1)N1CCC(CC1)Oc1cc(F)ccc1Cl Show InChI InChI=1S/C15H16ClFN4O/c1-10-9-18-20-15(19-10)21-6-4-12(5-7-21)22-14-8-11(17)2-3-13(14)16/h2-3,8-9,12H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149330 (US8962837, 17) Show SMILES FC(F)(F)c1ccc(Cl)c(OC2CCN(CC2)c2nccnn2)c1 Show InChI InChI=1S/C15H14ClF3N4O/c16-12-2-1-10(15(17,18)19)9-13(12)24-11-3-7-23(8-4-11)14-20-5-6-21-22-14/h1-2,5-6,9,11H,3-4,7-8H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149336 (US8962837, 30) Show SMILES Cc1cnc(nn1)N1CCC(CC1)Oc1cc(F)ccc1Cl Show InChI InChI=1S/C15H16ClFN4O/c1-10-9-18-15(20-19-10)21-6-4-12(5-7-21)22-14-8-11(17)2-3-13(14)16/h2-3,8-9,12H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149326 (US8962837, 11) Show SMILES Cn1ccnc(N2CCC(CC2)Oc2ccccc2C(F)(F)F)c1=O Show InChI InChI=1S/C17H18F3N3O2/c1-22-11-8-21-15(16(22)24)23-9-6-12(7-10-23)25-14-5-3-2-4-13(14)17(18,19)20/h2-5,8,11-12H,6-7,9-10H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149323 (US8962837, 7) Show SMILES Cn1cc(Cl)nc(N2CCC(CC2)Oc2ccccc2C(F)(F)F)c1=O Show InChI InChI=1S/C17H17ClF3N3O2/c1-23-10-14(18)22-15(16(23)25)24-8-6-11(7-9-24)26-13-5-3-2-4-12(13)17(19,20)21/h2-5,10-11H,6-9H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149343 (US8962837, 40) Show SMILES Cn1nccc(N2CCC(CC2)Oc2cc(ccc2Cl)C(F)(F)F)c1=O Show InChI InChI=1S/C17H17ClF3N3O2/c1-23-16(25)14(4-7-22-23)24-8-5-12(6-9-24)26-15-10-11(17(19,20)21)2-3-13(15)18/h2-4,7,10,12H,5-6,8-9H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149324 (US8962837, 8) Show SMILES Cn1cc(Cl)nc(N2CCC(CC2)Oc2cc(ccc2Cl)C(F)(F)F)c1=O Show InChI InChI=1S/C17H16Cl2F3N3O2/c1-24-9-14(19)23-15(16(24)26)25-6-4-11(5-7-25)27-13-8-10(17(20,21)22)2-3-12(13)18/h2-3,8-9,11H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150667 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CSCC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O6S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(34-15-17-8-6-5-7-9-17)22(35-18)24(31)29-20(25(32)33)12-13-36-4/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149334 (US8962837, 27) Show SMILES Cc1cnnc(n1)N1CCC(CC1)Oc1cc(ccc1Cl)C(F)(F)F Show InChI InChI=1S/C16H16ClF3N4O/c1-10-9-21-23-15(22-10)24-6-4-12(5-7-24)25-14-8-11(16(18,19)20)2-3-13(14)17/h2-3,8-9,12H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149345 (US8962837, Sterculic acid) Show SMILES CCCCCCCCC1=C(CCCCCCCC(O)=O)C1 |c:8| Show InChI InChI=1S/C19H34O2/c1-2-3-4-5-7-10-13-17-16-18(17)14-11-8-6-9-12-15-19(20)21/h2-16H2,1H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50366346 (CHEMBL1790477) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(=O)N[C@@H](CCSC)C(O)=O Show InChI InChI=1S/C19H36N4O5S2/c1-6-11(4)15(18(26)21-13(19(27)28)7-8-30-5)23-17(25)14(10(2)3)22-16(24)12(20)9-29/h10-15,29H,6-9,20H2,1-5H3,(H,21,26)(H,22,24)(H,23,25)(H,27,28)/t11-,12+,13+,14+,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149341 (US8962837, 37) Show SMILES CC1CN(CCC1Oc1cc(ccc1Cl)C(F)(F)F)c1nccnn1 Show InChI InChI=1S/C16H16ClF3N4O/c1-10-9-24(15-21-5-6-22-23-15)7-4-13(10)25-14-8-11(16(18,19)20)2-3-12(14)17/h2-3,5-6,8,10,13H,4,7,9H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149339 (US8962837, 35) Show SMILES [O-][N+](=O)c1ccccc1OC1CCN(CC1)c1nccnn1 Show InChI InChI=1S/C14H15N5O3/c20-19(21)12-3-1-2-4-13(12)22-11-5-9-18(10-6-11)14-15-7-8-16-17-14/h1-4,7-8,11H,5-6,9-10H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149332 (US8962837, 19) Show SMILES Cc1nnc(nc1C)N1CCC(CC1)Oc1cc(ccc1Cl)C(F)(F)F Show InChI InChI=1S/C17H18ClF3N4O/c1-10-11(2)23-24-16(22-10)25-7-5-13(6-8-25)26-15-9-12(17(19,20)21)3-4-14(15)18/h3-4,9,13H,5-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149329 (US8962837, 14) Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1nccnn1 Show InChI InChI=1S/C15H15F3N4O/c16-15(17,18)12-3-1-2-4-13(12)23-11-5-9-22(10-6-11)14-19-7-8-20-21-14/h1-4,7-8,11H,5-6,9-10H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149328 (US8962837, 13) Show SMILES Clc1ccccc1OC1CCN(CC1)c1nccnn1 Show InChI InChI=1S/C14H15ClN4O/c15-12-3-1-2-4-13(12)20-11-5-9-19(10-6-11)14-16-7-8-17-18-14/h1-4,7-8,11H,5-6,9-10H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149325 (US8962837, 9) Show SMILES Cc1ccccc1OC1CCN(CC1)c1nc(Cl)cn(C)c1=O Show InChI InChI=1S/C17H20ClN3O2/c1-12-5-3-4-6-14(12)23-13-7-9-21(10-8-13)16-17(22)20(2)11-15(18)19-16/h3-6,11,13H,7-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149322 (US8962837, 6) Show SMILES Cn1cc(Cl)nc(N2CCC(CC2)Oc2ccccc2Cl)c1=O Show InChI InChI=1S/C16H17Cl2N3O2/c1-20-10-14(18)19-15(16(20)22)21-8-6-11(7-9-21)23-13-5-3-2-4-12(13)17/h2-5,10-11H,6-9H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149344 (US8962837, 42) Show SMILES FC(F)(F)c1ccc(Cl)c(OC2CCN(C2)c2nccnn2)c1 Show InChI InChI=1S/C14H12ClF3N4O/c15-11-2-1-9(14(16,17)18)7-12(11)23-10-3-6-22(8-10)13-19-4-5-20-21-13/h1-2,4-5,7,10H,3,6,8H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149335 (US8962837, 28) Show SMILES Cc1cnnc(n1)N1CCC(CC1)Oc1ccccc1Cl Show InChI InChI=1S/C15H17ClN4O/c1-11-10-17-19-15(18-11)20-8-6-12(7-9-20)21-14-5-3-2-4-13(14)16/h2-5,10,12H,6-9H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149342 (US8962837, 38) Show SMILES CC1CN(CCC1Oc1cc(Cl)ccc1Cl)c1nccnn1 Show InChI InChI=1S/C15H16Cl2N4O/c1-10-9-21(15-18-5-6-19-20-15)7-4-13(10)22-14-8-11(16)2-3-12(14)17/h2-3,5-6,8,10,13H,4,7,9H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150666 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+,39?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150662 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20+,21+,22+,23+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150665 ((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CSCC[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O6S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(34-15-17-8-6-5-7-9-17)22(35-18)24(31)29-20(25(32)33)12-13-36-4/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19-,20-,21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150665 ((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CSCC[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O6S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(34-15-17-8-6-5-7-9-17)22(35-18)24(31)29-20(25(32)33)12-13-36-4/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19-,20-,21-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150662 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20+,21+,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150664 ((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19-,20-,21-,22-,39?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150663 ((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20-,21-,22-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150671 ((S)-2-(1-{(2R,6R)-6-[((R)-2-Amino-3-tert-butyldisu...) Show SMILES CC(C)C[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CCC1O)C(O)=O |w:6.6| Show InChI InChI=1S/C21H39N3O5S2/c1-12(2)9-16(20(27)28)24-13(3)18-17(25)8-7-14(29-18)10-23-19(26)15(22)11-30-31-21(4,5)6/h12,14-18,25H,7-11,22H2,1-6H3,(H,23,26)(H,27,28)/t14-,15+,16+,17?,18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.61E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150669 ((S)-2-(1-{(2R,3S,6S)-6-[((R)-2-Amino-3-tert-butyld...) Show SMILES CC(C)C[C@H](N=C(C)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C28H45N3O5S2/c1-18(2)14-23(27(33)34)31-19(3)25-24(35-16-20-10-8-7-9-11-20)13-12-21(36-25)15-30-26(32)22(29)17-37-38-28(4,5)6/h7-11,18,21-25H,12-17,29H2,1-6H3,(H,30,32)(H,33,34)/t21-,22-,23-,24-,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150668 ((S)-2-(1-{(2R,3S,6S)-6-[((R)-2-Amino-3-tert-butyld...) Show SMILES CSCC[C@H](N=C(C)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C27H43N3O5S3/c1-18(30-22(26(32)33)13-14-36-5)24-23(34-16-19-9-7-6-8-10-19)12-11-20(35-24)15-29-25(31)21(28)17-37-38-27(2,3)4/h6-10,20-24H,11-17,28H2,1-5H3,(H,29,31)(H,32,33)/t20-,21-,22-,23-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150663 ((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H43N3O6S2/c1-17(2)13-21(26(33)34)30-25(32)23-22(35-15-18-9-7-6-8-10-18)12-11-19(36-23)14-29-24(31)20(28)16-37-38-27(3,4)5/h6-10,17,19-23H,11-16,28H2,1-5H3,(H,29,31)(H,30,32)(H,33,34)/t19-,20-,21-,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150670 ((S)-2-(1-{(2R,3S,6R)-6-[((R)-2-Amino-3-tert-butyld...) Show SMILES CC(C)C[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C28H45N3O5S2/c1-18(2)14-23(27(33)34)31-19(3)25-24(35-16-20-10-8-7-9-11-20)13-12-21(36-25)15-30-26(32)22(29)17-37-38-28(4,5)6/h7-11,18,21-25H,12-17,29H2,1-6H3,(H,30,32)(H,33,34)/t21-,22+,23+,24+,25-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.64E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150672 ((S)-2-(1-{(2R,3S,6R)-6-[((R)-2-Amino-3-tert-butyld...) Show SMILES CSCC[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C27H43N3O5S3/c1-18(30-22(26(32)33)13-14-36-5)24-23(34-16-19-9-7-6-8-10-19)12-11-20(35-24)15-29-25(31)21(28)17-37-38-27(2,3)4/h6-10,20-24H,11-17,28H2,1-5H3,(H,29,31)(H,32,33)/t20-,21+,22+,23+,24-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150664 ((S)-2-({(2S,3S,6S)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19-,20-,21-,22-,39?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150671 ((S)-2-(1-{(2R,6R)-6-[((R)-2-Amino-3-tert-butyldisu...) Show SMILES CC(C)C[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CCC1O)C(O)=O |w:6.6| Show InChI InChI=1S/C21H39N3O5S2/c1-12(2)9-16(20(27)28)24-13(3)18-17(25)8-7-14(29-18)10-23-19(26)15(22)11-30-31-21(4,5)6/h12,14-18,25H,7-11,22H2,1-6H3,(H,23,26)(H,27,28)/t14-,15+,16+,17?,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150672 ((S)-2-(1-{(2R,3S,6R)-6-[((R)-2-Amino-3-tert-butyld...) Show SMILES CSCC[C@H](N=C(C)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O |w:6.6| Show InChI InChI=1S/C27H43N3O5S3/c1-18(30-22(26(32)33)13-14-36-5)24-23(34-16-19-9-7-6-8-10-19)12-11-20(35-24)15-29-25(31)21(28)17-37-38-27(2,3)4/h6-10,20-24H,11-17,28H2,1-5H3,(H,29,31)(H,32,33)/t20-,21+,22+,23+,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation by Protein Farnesyltransferase				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150666 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CS(=O)CC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O7S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(35-15-17-8-6-5-7-9-17)22(36-18)24(31)29-20(25(32)33)12-13-39(4)34/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+,39?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50150667 ((S)-2-({(2S,3S,6R)-6-[((R)-2-Amino-3-tert-butyldis...) Show SMILES CSCC[C@H](NC(=O)[C@H]1O[C@@H](CNC(=O)[C@@H](N)CSSC(C)(C)C)CC[C@@H]1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C26H41N3O6S3/c1-26(2,3)38-37-16-19(27)23(30)28-14-18-10-11-21(34-15-17-8-6-5-7-9-17)22(35-18)24(31)29-20(25(32)33)12-13-36-4/h5-9,18-22H,10-16,27H2,1-4H3,(H,28,30)(H,29,31)(H,32,33)/t18-,19+,20+,21+,22+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of [3H]GGPP incorporation by Protein Geranylgeranyl transferase type I				J Med Chem 47: 3920-3 (2004) Article DOI: 10.1021/jm049927q BindingDB Entry DOI: 10.7270/Q2FT8MT5
					More data for this Ligand-Target Pair